Dr. Mingtao Zhao Profile

Dr. Mingtao Zhao

Research Fellow at Johns Hopkins Univ

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Publications (15)

SPIE Journal Paper | 7 May 2014 Open Access

Robot-assisted three-dimensional registration for cochlear implant surgery using a common-path swept-source optical coherence tomography probe

Saumya Gurbani, Paul Wilkening, Mingtao Zhao, Berk Gonenc, Gyeong Woo Cheon, Iulian Iordachita, Wade Chien, Russell Taylor, John Niparko, Jin Kang

JBO, Vol. 19, Issue 05, 057004, (May 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.5.057004

KEYWORDS: Optical coherence tomography, Surgery, Image registration, Bone, Polishing, Electrodes, 3D image processing, Imaging systems, Tissues, 3D modeling

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Proceedings Article | 26 March 2013 Paper

Sapphire ball lensed fiber probe for common-path optical coherence tomography in ocular imaging and sensing

Mingtao Zhao, Yong Huang, Jin Kang

Proceedings Volume 8567, 856727 (2013) https://doi.org/10.1117/12.2005099

KEYWORDS: Optical coherence tomography, Sapphire, Single mode fibers, Retina, Gaussian beams, Imaging systems, Cornea, Vitreous, Surgery, Sensors

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Proceedings Article | 20 March 2013 Paper

Sensing and three-dimensional imaging of cochlea and surrounding temporal bone using swept source high-speed optical coherence tomography

Mingtao Zhao, Wade Chien, Russ Taylor, Iulian Iordachita, Yong Huang, John Niparko, Jin Kang

Proceedings Volume 8571, 857121 (2013) https://doi.org/10.1117/12.2007069

KEYWORDS: Optical coherence tomography, 3D image processing, Bone, Nerve, Sapphire, Imaging systems, Single mode fibers, Visualization, 3D scanning, Graphics processing units

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Proceedings Article | 8 March 2013 Paper

Sensing and three-dimensional OCT imaging of the cochlea and temporal bone: image-guided cochlear implantation

Mingtao Zhao, Wade Chien, Iulian Iordachita, Yong Huang, Russ Taylor, John Niparko, Jin Kang

Proceedings Volume 8565, 85651U (2013) https://doi.org/10.1117/12.2009401

KEYWORDS: Optical coherence tomography, Bone, Nerve, 3D image processing, Sapphire, Imaging systems, Single mode fibers, Robotics, Visualization, Head

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Proceedings Article | 8 March 2013 Paper

In-vivo and in-situ detection of atherosclerotic plaques using full-range complex-conjugate-free spectral domain optical coherence tomography in the murine carotid

Yong Huang, Robert Wicks, Kang Zhang, Mingtao Zhao, Betty Tyler, Lee Hwang, Gustavo Pradilla, Jin Kang

Proceedings Volume 8565, 85654P (2013) https://doi.org/10.1117/12.2001928

KEYWORDS: Optical coherence tomography, In vivo imaging, Visualization, Arteries, 3D image processing, Real time imaging, Neck, Surgery, Ultrasonography, Diagnostics

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Proceedings Article | 20 February 2009 Paper

Synthetic wavelength-based phase unwrapping in Fourier domain optical coherence tomography

Hansford Hendargo, Mingtao Zhao, Neal Shepherd, Joseph Izatt

Proceedings Volume 7168, 71681C (2009) https://doi.org/10.1117/12.808077

KEYWORDS: Optical coherence tomography, Microscopy, Doppler tomography, Phase interferometry, Phase measurement, Signal to noise ratio, Refractive index, Spectroscopy, Coherence (optics), Polarization

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Phase-sensitive adjuncts to optical coherence tomography (OCT) including Doppler and polarization-sensitive implementations allow for quantitative depth-resolved measurements of sample structure and dynamics including fluid flows and orientation of birefringent structures. The development of Fourier-domain OCT (FDOCT), particularly spectrometer-based spectral-domain systems with no moving parts (spectral-domain OCT or SDOCT), have greatly enhanced the phase stability of OCT systems particularly when implemented in a common-path geometry. The latter combination has given rise to a new class of nm-scale sensitive quantitative phase microscopies we have termed spectral domain phase microscopy. However, the phase information in all of these techniques suffers from a 2π ambiguity that limits resolvable pathlength differences to less than half the source center wavelength. This is problematic for situations such as cellular imaging, Doppler velocimetry, or polarization sensitive applications where it may be necessary to monitor sample profiles, displacements, phase differences, or refractive index variations which vary rapidly in space or time. A technique previously introduced in phase shifting interferometry uses phase information from multiple wavelengths to overcome this limitation. We show that by appropriate spectral windowing of the broadband light source already used in OCT, particularly by reshaping the source spectrum about two different center wavelengths, the resulting phase variation may be cast in terms of a much longer synthetic wavelength chosen to span the phase variation of interest. We show theoretically that the optimal choice of synthetic wavelength depends upon a tradeoff between the minimum resolvable phase and the length of unambiguous phase measurement. We demonstrate this technique using a broadband source centered at 790 nm by correctly reconstructing the phase profile from a phantom sample containing multiple 2π wrapping artifacts at the center wavelength and compare our result with atomic force microscopy.

SPIE Journal Paper | 1 July 2007 Open Access

Real-time spectral domain Doppler optical coherence tomography and investigation of human retinal vessel autoregulation

Bradley Bower, Mingtao Zhao, Robert Zawadzki, Joseph Izatt

JBO, Vol. 12, Issue 04, 041214, (July 2007) https://doi.org/10.1117/12.10.1117/1.2772877

KEYWORDS: Doppler effect, Doppler tomography, Oxygen, Optical coherence tomography, Data acquisition, Imaging systems, Biomedical optics, Sensors, Coherence (optics), Image processing

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Proceedings Article | 7 February 2007 Paper

Complex-conjugate-resolved retinal SDOCT using integrating buckets

Yuankai Tao, Mingtao Zhao, Joseph Izatt

Proceedings Volume 6429, 64290W (2007) https://doi.org/10.1117/12.704729

KEYWORDS: Modulation, Phase shift keying, Retinal scanning, Interferometry, Imaging systems, Mirrors, Head, Retina, Ferroelectric materials, In vivo imaging

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Proceedings Article | 7 March 2006 Paper

3D OCT imaging in clinical settings: toward quantitative measurements of retinal structures

Robert Zawadzki, Alfred Fuller, Mingtao Zhao, David Wiley, Stacey Choi, Bradley Bower, Bernd Hamann, Joseph Izatt, John Werner

Proceedings Volume 6138, 613803 (2006) https://doi.org/10.1117/12.647567

KEYWORDS: Image segmentation, Optical coherence tomography, 3D image processing, Eye, 3D acquisition, Visualization, Retina, 3D metrology, Data acquisition, 3D visualizations

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Proceedings Article | 7 March 2006 Paper

Adaptive optics-optical coherence tomography for in vivo retinal imaging: effects of spectral bandwidth on image quality

Robert Zawadzki, Steven Jones, Mingtao Zhao, Stacey Choi, Sophie Laut, Scot Olivier, Joseph Izatt, John Werner

Proceedings Volume 6138, 61381X (2006) https://doi.org/10.1117/12.647540

KEYWORDS: Optical coherence tomography, Adaptive optics, Adaptive optics optical coherence tomography, Wavefronts, Light sources, Eye, Mirrors, Wavefront sensors, Retinal scanning, Deformable mirrors

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Proceedings Article | 20 February 2006 Paper

Adaptive optics/optical coherence tomography for in vivo retinal imaging: comparative analysis of two wavefront correctors

Robert Zawadzki, Steven Jones, Mingtao Zhao, Stacey Choi, Sophie Laut, Scot Olivier, Joseph Izatt, John Werner

Proceedings Volume 6079, 607908 (2006) https://doi.org/10.1117/12.647568

KEYWORDS: Adaptive optics, Wavefronts, Mirrors, Optical coherence tomography, Adaptive optics optical coherence tomography, Deformable mirrors, Eye, Microelectromechanical systems, Wavefront sensors, Retinal scanning

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Proceedings Article | 20 February 2006 Paper

Investigation of retinal vessel autoregulation using real-time spectral domain Doppler optical coherence tomography

Bradley Bower, Mingtao Zhao, Joseph Izatt

Proceedings Volume 6079, 60790D (2006) https://doi.org/10.1117/12.649192

KEYWORDS: Doppler tomography, Optical coherence tomography, Oxygen, Doppler effect, Data acquisition, Imaging systems, Laser Doppler velocimetry, 3D volumetric displays, Image processing, Arteries

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Proceedings Article | 7 October 2005 Paper

Adaptive-optics optical coherence tomography for high-resolution and high-speed in vivo retinal imaging

Robert Zawadzki, Stacey Choi, Sophie Laut, John Werner, Steven Jones, Scot Olivier, Mingtao Zhao, Bradley Bower, Joseph Izatt

Proceedings Volume 5861, 586104 (2005) https://doi.org/10.1117/12.632962

KEYWORDS: Optical coherence tomography, Adaptive optics, Eye, Adaptive optics optical coherence tomography, Imaging systems, In vivo imaging, Retinal scanning, Image resolution, Deformable mirrors, Retina

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Proceedings Article | 18 April 2005 Paper

Exposure time dependence of image quality in high-speed retinal in vivo Fourier-domain OCT

Robert Zawadzki, Bradley Bower, Mingtao Zhao, Marinko Sarunic, Sophie Laut, John Werner, Joseph Izatt

Proceedings Volume 5688, (2005) https://doi.org/10.1117/12.591660

KEYWORDS: Optical coherence tomography, Image quality, In vivo imaging, Signal to noise ratio, Mirrors, Spectroscopy, Charge-coupled devices, Retina, Eye, Imaging systems

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Proceedings Article | 13 April 2005 Paper

Rapid volumetric imaging of the human retina in vivo using a low-cost spectral domain optical coherence tomography system

Bradley Bower, Mingtao Zhao, Yimin Wang, Albert Chu, Robert Zawadzki, Marinko Sarunic, Joseph Izatt

Proceedings Volume 5690, (2005) https://doi.org/10.1117/12.592874

KEYWORDS: Optical coherence tomography, Dispersion, Retina, Imaging systems, In vivo imaging, Reflectors, Data acquisition, Optic nerve, Head, Spectroscopy

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Showing 5 of 15 publications

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