Prof. Qiyin Fang Profile

Prof. Qiyin Fang

Professor and Canada Research Chair at McMaster Univ

Publications (38)

SPIE Journal Paper | 23 August 2023 Open Access

Multivariate analysis of breast tissue using optical parameters extracted from a combined time-resolved fluorescence and diffuse reflectance system for tumor margin detection

Erica Dao, Gabriela Gohla, Phillip Williams, Peter Lovrics, Fares Badr, Qiyin Fang, Thomas Farrell, Michael Farquharson

JBO, Vol. 28, Issue 08, 085001, (August 2023) https://doi.org/10.1117/12.10.1117/1.JBO.28.8.085001

KEYWORDS: Tumors, Tissues, Adipose tissue, Breast, Tissue optics, Modeling, Biological samples, Reflectivity, Cancer detection, Principal component analysis

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Proceedings Article | 6 March 2021 Presentation

A real-time endoscope tip motion tracker

Ian Phillips, David Armstrong, Qiyin Fang

Proceedings Volume 11631, 116310Z (2021) https://doi.org/10.1117/12.2582883

KEYWORDS: Endoscopes, Motion measurement, Cameras, Tumors, Endoscopy, Video, Tissues, Surgery, Prototyping, Natural surfaces

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Proceedings Article | 16 March 2020 Paper

Spectral assessment of radiation therapy-induced skin erythema

Ramy Abdlaty, Lillian Doerwald, Joseph Hayward, Qiyin Fang

Proceedings Volume 11316, 1131619 (2020) https://doi.org/10.1117/12.2541515

KEYWORDS: Skin, Radiotherapy, Reflectivity, Visualization, Skin cancer, Hyperspectral imaging, Tissue optics, Cancer, Diffuse reflectance spectroscopy, Data acquisition

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Proceedings Article | 17 February 2020 Presentation + Paper

A multiplexed confocal FLIM microscope with 4-taps time-gated imager

Morgan Richards, Yuya Shirakawa, Fares Badr, Keiichiro Kagawa, Shoji Kawahito, Qiyin Fang

Proceedings Volume 11245, 1124512 (2020) https://doi.org/10.1117/12.2550208

KEYWORDS: Confocal microscopy, Imaging systems, Fluorescence lifetime imaging, Microscopes, Sensors, Multiplexing, Luminescence, Relays, Microlens array, Biomedical optics

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Proceedings Article | 31 July 2019 Paper

Investigating Bcl-2 family protein-protein interactions using a high-speed multiplexing confocal FLIM microscope

Nehad Hirmiz, Anthony Tsikouras, Elizabeth Osterlund, Morgan Richards, Jessica Kun, David Andrews, Qiyin Fang

Proceedings Volume 11076, 1107617 (2019) https://doi.org/10.1117/12.2526906

KEYWORDS: Confocal microscopy, Fluorescence lifetime imaging, Proteins, Multiplexing, Fluorescence resonance energy transfer, Microscopes, Microscopy

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Proceedings Article | 22 July 2019 Paper

Detection of trichomonal vaginalis through lensless optofluidic microscopy

Jessica Kun, Marek Smieja, Leyla Soleymani, Qiyin Fang

Proceedings Volume 11076, 110761A (2019) https://doi.org/10.1117/12.2526893

KEYWORDS: Sensors, Optofluidics, Microscopy, CMOS sensors, Microfluidics, Video, Glasses, Point-of-care devices, Image sensors, Optical sensors

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Proceedings Article | 2 July 2019 Open Access

Experiential learning of data acquisition and sensor networks with a cloud computing platform

Eric Mahoney, Colleen Chau, Qiyin Fang

Proceedings Volume 11143, 111433X (2019) https://doi.org/10.1117/12.2535399

KEYWORDS: Data acquisition, Sensors, Humidity, Statistical analysis, Clouds, Temperature metrology, Temperature sensors, Data communications, Environmental sensing, Sensing systems

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Proceedings Article | 4 March 2019 Presentation + Paper

Radiation-therapy-induced erythema: comparison of spectroscopic diffuse reflectance measurements and visual assessment

Ramy Abdlaty, Lilian Doerwald, Joseph Hayward, Qiyin Fang

Proceedings Volume 10952, 109520H (2019) https://doi.org/10.1117/12.2506306

KEYWORDS: Skin, Radiotherapy, Visualization, Diffuse reflectance spectroscopy, Reflectivity, Reflectance spectroscopy, Skin cancer, Visible radiation, Spectroscopy, Radiation effects

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Proceedings Article | 27 February 2019 Paper

Acousto-optic tunable filter-based hyperspectral imaging system characterization

Ramy Abdlaty, Qiyin Fang

Proceedings Volume 10870, 108700Y (2019) https://doi.org/10.1117/12.2506318

KEYWORDS: Imaging systems, Hyperspectral imaging, Acousto-optics, Tunable filters, Image filtering, Infrared imaging, Infrared radiation, Computing systems, CMOS cameras, Reflectors

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Proceedings Article | 14 March 2018 Presentation

Bovine cortical bone ablation by femtosecond laser (Conference Presentation)

Fahad Aljekhedab, Wenbin Zhang, Jonathan Favero, Harold Haugen, Gregory Wohl, Qiyin Fang

Proceedings Volume 10473, 104730F (2018) https://doi.org/10.1117/12.2289331

KEYWORDS: Laser ablation, Bone, Femtosecond phenomena, Laser cutting, Ultrafast phenomena, Laser therapeutics, Surgery, Laser applications, Laser tissue interaction, Tissues

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Proceedings Article | 9 March 2018 Paper

Hyperspectral imaging: comparison of acousto-optic and liquid crystal tunable filters

Ramy Abdlaty, Samir Sahli, Joseph Hayward, Qiyin Fang

Proceedings Volume 10573, 105732P (2018) https://doi.org/10.1117/12.2282532

KEYWORDS: Tunable filters, Optical filters, Acousto-optics, Crystals, Spectral resolution, Hyperspectral imaging, Sensors, Reflectivity, Spatial resolution

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Proceedings Article | 24 February 2017 Paper

Hyperspectral image processing for detection and grading of skin erythema

Ali Madooei, Ramy Mohammed Abdlaty, Lilian Doerwald-Munoz, Joseph Hayward, Mark Drew, Qiyin Fang, Josiane Zerubia

Proceedings Volume 10133, 1013322 (2017) https://doi.org/10.1117/12.2254132

KEYWORDS: Image processing, Hyperspectral imaging, Skin, RGB color model, Cameras, Imaging systems, Sensors, Visualization, Radiotherapy, Medical imaging

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SPIE Journal Paper | 3 February 2017 Open Access

Dual-modality optical biopsy of glioblastomas multiforme with diffuse reflectance and fluorescence: ex vivo retrieval of optical properties

Vinh Nguyen Du Le, John Provias, Naresh Murty, Michael Patterson, Zhaojun Nie, Joseph Hayward, Thomas Farrell, William McMillan, Wenbin Zhang, Qiyin Fang

JBO, Vol. 22, Issue 02, 027002, (February 2017) https://doi.org/10.1117/12.10.1117/1.JBO.22.2.027002

KEYWORDS: Luminescence, Optical properties, Tissues, Diffuse reflectance spectroscopy, Brain, Tumors, Absorption, Biopsy, Scattering, Biomedical optics

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SPIE Journal Paper | 22 December 2015 Open Access

Experimental recovery of intrinsic fluorescence and fluorophore concentration in the presence of hemoglobin: spectral effect of scattering and absorption on fluorescence

Vinh Nguyen Du Le, Michael Patterson, Thomas Farrell, Joseph Hayward, Qiyin Fang

JBO, Vol. 20, Issue 12, 127003, (December 2015) https://doi.org/10.1117/12.10.1117/1.JBO.20.12.127003

KEYWORDS: Luminescence, Absorption, Scattering, Tissues, Optical fibers, Magnesium, Mie scattering, Optical properties, Photons, Calibration

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SPIE Journal Paper | 19 March 2015 Open Access

5-aminolevulinic acid induced protoporphyrin IX as a fluorescence marker for quantitative image analysis of high-grade dysplasia in Barrett’s esophagus cellular models

Shu-Chi Yeh, Samir Sahli, David Andrews, Michael Patterson, David Armstrong, John Provias, Qiyin Fang

JBO, Vol. 20, Issue 03, 036010, (March 2015) https://doi.org/10.1117/12.10.1117/1.JBO.20.3.036010

KEYWORDS: Luminescence, Image segmentation, 3D modeling, Feature extraction, Esophagus, Image classification, Photodynamic therapy, Feature selection, Binary data, Image analysis

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SPIE Journal Paper | 11 February 2015 Open Access

5-aminolevulinic acid for quantitative seek-and-treat of high-grade dysplasia in Barrett’s esophagus cellular models

Shu-Chi Yeh, Celine Ling, David Andrews, Michael Patterson, Kevin Diamond, Joseph Hayward, David Armstrong, Qiyin Fang

JBO, Vol. 20, Issue 02, 028002, (February 2015) https://doi.org/10.1117/12.10.1117/1.JBO.20.2.028002

KEYWORDS: Photodynamic therapy, Luminescence, Esophagus, Cell death, Biopsy, Control systems, Error analysis, 3D modeling, Toxicity, Tissue optics

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SPIE Journal Paper | 11 October 2013 Open Access

Fiber-optic probe design and optical property recovery algorithm for optical biopsy of brain tissue

Derek Cappon, Thomas Farrell, Qiyin Fang, Joseph Hayward

JBO, Vol. 18, Issue 10, 107004, (October 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.10.107004

KEYWORDS: Monte Carlo methods, Optical properties, Reflectivity, Tissue optics, Sensors, Photons, Optical fibers, Fiber optics, Brain, Detection and tracking algorithms

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SPIE Journal Paper | 3 September 2013 Open Access

Hyperspectral fluorescence lifetime imaging for optical biopsy

Zhaojun Nie, Ran An, Joseph Hayward, Thomas Farrell, Qiyin Fang

JBO, Vol. 18, Issue 09, 096001, (September 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.9.096001

KEYWORDS: Luminescence, Fluorescence lifetime imaging, Biopsy, Tissues, Hyperspectral imaging, Biomedical optics, Skin, Tissue optics, Data acquisition, Calibration

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SPIE Journal Paper | 24 July 2013 Open Access

Ultrafast laser ablation and machining large-size structures on porcine bone

Ran An, Ghadeer Khadar, Emilia Wilk, Brent Emigh, Harold Haugen, Gregory Wohl, Brett Dunlop, Mehran Anvari, Joseph Hayward, Qiyin Fang

JBO, Vol. 18, Issue 07, 070504, (July 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.7.070504

KEYWORDS: Laser ablation, Bone, Ultrafast lasers, Laser therapeutics, Laser tissue interaction, Computed tomography, Surgery, Physics, Ultrafast phenomena, Tissues

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SPIE Journal Paper | 27 February 2012 Open Access

Porcine cortical bone ablation by ultrashort pulsed laser irradiation

Brent Emigh, Joseph Hayward, Ran An, Eugene Hsu, Travis Crawford, Harold Haugen, Gregory Wohl, Qiyin Fang

JBO, Vol. 17, Issue 02, 028001, (February 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.2.028001

KEYWORDS: Laser ablation, Bone, Laser damage threshold, Pulsed laser operation, Tissues, Laser irradiation, Laser tissue interaction, Physics, Surface finishing, Polishing

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SPIE Journal Paper | 1 June 2011 Open Access

Development of a catadioptric endoscope objective with forward and side views

Roy Chih Wang, Qiyin Fang, M. Jamal Deen, David Armstrong

JBO, Vol. 16, Issue 06, 066015, (June 2011) https://doi.org/10.1117/12.10.1117/1.3593148

KEYWORDS: Endoscopes, Mirrors, Modulation transfer functions, Prototyping, Lens design, Combined lens-mirror systems, Objectives, Monte Carlo methods, Endoscopy, Imaging systems

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SPIE Journal Paper | 1 March 2010 Open Access

Intraoperative delineation of primary brain tumors using time-resolved fluorescence spectroscopy

Pramod Butte, Fang Qiyin, Jo Javier, William Yong, Brian Pikul, Keith Black, Laura Marcu

JBO, Vol. 15, Issue 02, 027008, (March 2010) https://doi.org/10.1117/12.10.1117/1.3374049

KEYWORDS: Luminescence, Brain, Tumors, Tissues, Tissue optics, In vivo imaging, Surgery, Spectroscopy, Fluorescence spectroscopy, Biopsy

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Proceedings Article | 8 March 2007 Paper

Characterization of time-domain fluorescence properties of typical photosensitizers for photodynamic therapy

Jennifer Russell, Kevin Diamond, Tony Collins, Mark Weston, Jonathan Lovell, Joseph Hayward, Tom Farrell, Michael Patterson, Qiyin Fang

Proceedings Volume 6427, 64270G (2007) https://doi.org/10.1117/12.697638

KEYWORDS: Luminescence, Photodynamic therapy, Fluorescence lifetime imaging, Imaging spectroscopy, Single photon, In vivo imaging, Tumors, In vitro testing, Confocal microscopy, Tissue optics

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SPIE Journal Paper | 1 March 2006 Open Access

Laguerre-based method for analysis of time-resolved fluorescence data: application to in-vivo characterization and diagnosis of atherosclerotic lesions

Javier Jo, Qiyin Fang, Thanassis Papaioannou, J. Dennis Baker, Amir Dorafshar, Todd Reil, Jianhua Qiao, Michael Fishbein, Julie Freischlag, Laura Marcu

JBO, Vol. 11, Issue 02, 021004, (March 2006) https://doi.org/10.1117/12.10.1117/1.2186045

KEYWORDS: Time resolved spectroscopy, Luminescence, Statistical analysis, Principal component analysis, Tissues, Surface plasmons, In vivo imaging, Deconvolution, Biological research, Spectroscopy

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Proceedings Article | 25 February 2006 Paper

Packaging and characteristics of a microfluorescence spectroscopy analyzer

J. Lo, Q. Fang, W. Pang, T. Papaioannou, Q. Shui, E. Kim, M. Gundersen, L. Marcu

Proceedings Volume 6080, 60800H (2006) https://doi.org/10.1117/12.649297

KEYWORDS: Packaging, Microelectromechanical systems, Sensors, Silicon, Mirrors, Spectroscopy, Diffraction gratings, Semiconducting wafers, Monochromators, Actuators

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Proceedings Article | 22 February 2006 Paper

Detection of high-risk atherosclerotic lesions by time-resolved fluorescence spectroscopy based on the Laguerre deconvolution technique

Javier Jo, Qiyin Fang, Thanassis Papaioannou, Jianhua Qiao, M. Fishbein, B. Beseth, A. Dorafshar, T. Reil, D. Baker, J. Freischlag, L. Marcu

Proceedings Volume 6078, 60782H (2006) https://doi.org/10.1117/12.647560

KEYWORDS: Luminescence, Deconvolution, Tissues, Spectroscopy, Laser induced fluorescence, Inflammation, Fluorescence spectroscopy, Time resolved spectroscopy, Data analysis, In vivo imaging

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Proceedings Article | 29 March 2005 Paper

Picosecond fluorescence lifetime imaging microscope for imaging of living glioma cells

Qiyin Fang, Jingjing Wang, Yinghua Sun, Thomas Vernier, Thanassis Papaioannou, Javier Jo, Mya Thu, Martin Gundersen, Laura Marcu

Proceedings Volume 5699, (2005) https://doi.org/10.1117/12.592474

KEYWORDS: Luminescence, Fluorescence lifetime imaging, Microscopes, Picosecond phenomena, Semiconductor lasers, Microscopy, Imaging systems, Rhodamine, Cameras, Optical filters

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Proceedings Article | 29 March 2005 Paper

Multiphoton, confocal, and lifetime microscopy for molecular imaging in cartilage

Sebastian Wachsmann-Hogiu, Deborah Krakow, Veneta Kirilova, Daniel Cohn, Cristina Bertolotto, Dora Acuna, Qiyin Fang, Nikola Krivorov, Daniel Farkas

Proceedings Volume 5699, (2005) https://doi.org/10.1117/12.597670

KEYWORDS: Confocal microscopy, Luminescence, Fluorescence resonance energy transfer, Cartilage, Proteins, Fluorescence lifetime imaging, Multiphoton microscopy, Tissues, Microscopy, Molecular imaging

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Proceedings Article | 13 July 2004 Paper

Validation of a time-resolved fluorescence spectroscopy apparatus in a rabbit atherosclerosis model

Qiyin Fang, Javier Jo, Thanassis Papaioannou, Amir Dorafshar, Todd Reil, Jian-Hua Qiao, Michael Fishbein, Julie Freischlag, Laura Marcu

Proceedings Volume 5312, (2004) https://doi.org/10.1117/12.529677

KEYWORDS: Luminescence, Time resolved spectroscopy, In vivo imaging, Fiber optics, Foam, Fluorescence spectroscopy, Data acquisition, Tissues, Signal to noise ratio, Spectroscopes

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Proceedings Article | 13 July 2004 Paper

Laguerre nonparametric deconvolution technique of time-resolved fluorescence data: application to the prediction of concentrations in a mixture of biochemical components

Javier Jo, Qiyin Fang, Thanasis Papaioannou, Laura Marcu

Proceedings Volume 5326, (2004) https://doi.org/10.1117/12.527787

KEYWORDS: Luminescence, Deconvolution, Data modeling, Time resolved spectroscopy, Biological research, Error analysis, Pulsed laser operation, Solids, Statistical modeling, Rhodamine B

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SPIE Journal Paper | 1 July 2004 Open Access

Fast model-free deconvolution of fluorescence decay for analysis of biological systems

Javier Jo, Qiyin Fang, Thanassis Papaioannou, Laura Marcu

JBO, Vol. 9, Issue 04, (July 2004) https://doi.org/10.1117/12.10.1117/1.1752919

KEYWORDS: Luminescence, Deconvolution, Data modeling, Biological research, Time resolved spectroscopy, Tissues, Complex systems, Pulsed laser operation, Solids, Bioalcohols

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Proceedings Article | 8 October 2003 Paper

Lifetime fluorescence apparatus for clinical investigations of tissues

Laura Marcu, Qiyin Fang, Thanassis Papaioannou, Javier Jo, Russel Vaitha, Kumar Shastry

Proceedings Volume 5141, (2003) https://doi.org/10.1117/12.501020

KEYWORDS: Luminescence, Tissues, Fiber optics, Time resolved spectroscopy, Deconvolution, In vivo imaging, Fluorescence spectroscopy, Light sources, Spectroscopes, Diagnostics

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Proceedings Article | 22 July 2003 Paper

Compact time-resolved laser-induced fluorescence spectroscopic system for clinical investigations of diseased tissues

Qiyin Fang, Thanassis Papaioannou, Javier Jo, Russel Vaitha, Kumar Shastry, Laura Marcu

Proceedings Volume 4958, (2003) https://doi.org/10.1117/12.476133

KEYWORDS: Luminescence, Time resolved spectroscopy, Laser induced fluorescence, Data acquisition, Spectrographs, Fluorescence spectroscopy, Fiber optics, Calibration, Signal to noise ratio, Pulsed laser operation

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Proceedings Article | 22 July 2003 Paper

Performance evaluation of fiber optic probes for tissue lifetime fluorescence spectroscopy

Thanassis Papaioannou, Norris Preyer, Qiyin Fang, Hamza Kurt, Michael Carnohan, Russel Ross, Adam Brightwell, Greg Cottone, Linda Jones, Laura Marcu

Proceedings Volume 4958, (2003) https://doi.org/10.1117/12.476141

KEYWORDS: Monte Carlo methods, Fiber optics, Tissues, Tissue optics, Fluorescence spectroscopy, Photons, Diagnostics, Diffuse reflectance spectroscopy, Biomedical optics, Spectroscopy

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Proceedings Article | 21 May 2001 Paper

Tattoo removal in micropigs with low-energy pulses from a Q-switched Nd:YAG laser at 1064 nm

Xin-Hua Hu, W. Wooden, Mickael Cariveau, Qiyin Fang, J. Bradfield, Gerhard Kalmus, S. Vore, Y. Sun

Proceedings Volume 4244, (2001) https://doi.org/10.1117/12.427822

KEYWORDS: Skin, Laser therapeutics, Laser ablation, Q switched lasers, Laser tissue interaction, Nd:YAG lasers, Pulsed laser operation, Laser vision correction, Tissues, Surgery

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Proceedings Article | 13 June 2000 Paper

Ablation of skin tissue by nanosecond laser pulses at 1064, 532, 266, and 213 nm

Xin-Hua Hu, Qiyin Fang, Mickael Cariveau, X. Pan, Gerhard Kalmus

Proceedings Volume 3914, (2000) https://doi.org/10.1117/12.388028

KEYWORDS: Laser ablation, Skin, Tissues, Laser tissue interaction, Tissue optics, Pulsed laser operation, Electrons, Electromagnetism, Natural surfaces, Absorption

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Proceedings Article | 18 August 1995 Paper

Study of resistance against photorefractive light-induced scattering in LiNbO3:Fe,Mg crystals

Guangyin Zhang, Jingjun Xu, Simin Liu, Qian Sun, Guoquan Zhang, Qiyin Fang, Chaoli Ma

Proceedings Volume 2529, (1995) https://doi.org/10.1117/12.217010

KEYWORDS: Light scattering, Crystals, Scattering, Magnesium, Resistance, Lithium, Modulation, Crystallography, Phase shift keying, Laser scattering

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Proceedings Article | 18 August 1995 Paper

One-way aberration-free image communication through a phase-disturbing medium using photorefractive four-wave mixing

Jingjun Xu, Guangyin Zhang, Simin Liu, Qian Sun, Guoquan Zhang, Qiyin Fang, Chaoli Ma

Proceedings Volume 2529, (1995) https://doi.org/10.1117/12.217016

KEYWORDS: Four wave mixing, Crystals, Image processing, Reflectivity, Phase conjugation, Two wave mixing, Information operations, Laser development, Distortion

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Showing 5 of 38 publications

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