Mr. Roman Kalmykov Profile

Roman Kalmykov

at Saratov State Medical Univ

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Proceedings Article | 19 February 2018 Paper

Corneal permeability for cement dust: prognosis for occupational safety

R. Kalmykov, D. Popova, T. Kamenskikh, E. Genina, V. Tuchin, A. Bashkatov

Proceedings Volume 10474, 104742E (2018) https://doi.org/10.1117/12.2297042

KEYWORDS: Cornea, Cements, Signal attenuation, Eye, Particles, Scattering, Diffusion, Optical coherence tomography, Tissue optics, Refractive index

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The high dust content in air of a working zone causes prevalence of pathologies of the anterior segment of the eye of workers of cement production. Therefore, studying of features of cement dust impact on structure of a cornea and development of ways of eye protection from this influence is relevant. In this work experimental studies were carried out with twenty eyes of ten rabbits. OCTtomography was used to monitor the light attenuation coefficient of the cornea in vitro during the permeability of cement dust and/or keratoprotector (Systein Ultra). The permeability coefficients of the cornea for water, cement dust and keratoprotector were measured. A computer model allowing one to analyze the diffusion of these substances in the eye cornea was developed. It was shown that 1) the cement dust falling on the eye cornea caused pronounced dehydration of the tissue (thickness decreasing) and led to the increase of the attenuation coefficient, which could affect the deterioration of the eyesight of workers in the conditions of cement production; 2) the application of the keratoprotector to the eye cornea when exposed by cement dust, slowed significantly the dehydration process and did not cause the increase of the attenuation coefficient that characterized the stabilization of visual functions. At this, the keratoprotector itself did not cause dehydration and led to the decrease of the attenuation coefficient, which could allow it to be used for a long time in the order to protect the organ of vision from the negative effects of cement dust.

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