Mr. Sean Paulsen Profile

Sean Paulsen

at Simon Fraser Univ

SPIE Involvement:

Author

Publications (1)

This will count as one of your downloads.

You will have access to both the presentation and article (if available).

DOWNLOAD NOW

This content is available for download via your institution's subscription. To access this item, please sign in to your personal account.

Email or Username Forgot your username?

Password Forgot your password?

Show

Keep me signed in

No SPIE account? Create an account

Proceedings Article | 25 February 2020 Presentation + Paper

Characterizing long lived intralipid-infused tissue phantoms scattering using imaging sensors

Glenn Chapman, Sean Paulsen, Yutian Zhang

Proceedings Volume 11238, 112380S (2020) https://doi.org/10.1117/12.2548689

KEYWORDS: Scattering, Laser scattering, Light scattering, Solids, Cameras, Tissue optics, Tissues, Scatter measurement, Anisotropy, Polymethylmethacrylate

Read Abstract +

Since regular biological tissue’s optical characteristics are unstable building long lived test phantoms that simulate their scattering characteristics are needed for testing optical methods of imaging through tissue. Our ongoing work developed a methodology to build long term stable phantoms with lifetimes >6 years which can be tuned to maintaining optical characteristics mimicing skin characteristics and a rapid technique to measure the scattering coefficients μ_s and anisotropy factor g. Our test phantoms employ intralipid-infused agar layers 1 to 8 mm thick. Agra can take a wide range of intralipid concentrations enabling the building phantoms of a large range of scattering parameters with typical values of μ_s=20cm^-1, g=0.95. Encapsulating the intralipid-infused agar within a clear polymer has proved to stabilize these for long lifetimes and allows creation of varying thicknesses, scattering characteristics and shapes. We developed a rapid technique where the light from a laser beam passing perpendicular through the test phantom is captured using a 36×24mm digital camera sensor. This gathers ~6×10⁶ measurements over a ±12° range, giving ~20,000 points each at 2300 angular bins of 0.005° . A Matlab program identifies the scattering center and data points for each angular position. Using a HenyeyGreenstein two-term model a nonlinear curve fitting extracts pairs of HG weighing factors, µs and g parameters. Fit results show extremely high statistical significance with exceedingly small deviation from the HG model for multiple wavelengths (currently 533, 632, 670 nm lasers and a supercontinuum laser at 650, 700,750 nm) for several test phantoms.

My Library

You currently do not have any folders to save your paper to! Create a new folder below.

Folder Name

Folder Description

View contact details

UPDATE YOUR PROFILE

Is this your profile? Update it now.

Sign into your SPIE.org account

Don’t have a profile and want one?

Create an account on SPIE.org

Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks. You are receiving this notice because your organization may not have SPIE eBooks access.*

*Shibboleth/Open Athens users─please sign in to access your institution's subscriptions.

To obtain this item, you may purchase the complete book in print or electronic format on SPIE.org.

ORGANIZATIONAL
Sign in with credentials provided by your organization.

Organizational Username

Organizational Password

Show/Hide Password

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members:

Non-members: ADD TO CART

Keywords/Phrases

Search In:

Publication Years