Dr. Susana Celestino Marcos Profile

Dr. Susana Celestino Marcos

at Instituto de Optica "Daza de Valdes"

SPIE Involvement:

Author

Publications (5)

SPIE Journal Paper | 14 May 2014 Open Access

Special Section Guest Editorial: Human Vision

Eli Peli, Susana Marcos, Stephen Burns, Joyce Farrell

OE, Vol. 53, Issue 06, 061701, (May 2014) https://doi.org/10.1117/12.10.1117/1.OE.53.6.061701

KEYWORDS: Human vision and color perception, Visual optics, Imaging systems, Eye, Optical engineering, Medical research, Biomedical optics, Systems engineering, Visual system, Light emitting diodes

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Proceedings Article | 26 February 2014 Paper

Corneal biomechanical properties from air-puff corneal deformation imaging

Susana Marcos, Sabine Kling, Nandor Bekesi, Carlos Dorronsoro

Proceedings Volume 8946, 894609 (2014) https://doi.org/10.1117/12.2047290

KEYWORDS: Cornea, In vivo imaging, Eye, Optical coherence tomography, Imaging systems, Finite element methods, Tissues, Tissue optics, Mercury, Ultraviolet radiation

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The combination of air-puff systems with real-time corneal imaging (i.e. Optical Coherence Tomography (OCT), or Scheimpflug) is a promising approach to assess the dynamic biomechanical properties of the corneal tissue in vivo. In this study we present an experimental system which, together with finite element modeling, allows measurements of corneal biomechanical properties from corneal deformation imaging, both ex vivo and in vivo. A spectral OCT instrument combined with an air puff from a non-contact tonometer in a non-collinear configuration was used to image the corneal deformation over full corneal cross-sections, as well as to obtain high speed measurements of the temporal deformation of the corneal apex. Quantitative analysis allows direct extraction of several deformation parameters, such as apex indentation across time, maximal indentation depth, temporal symmetry and peak distance at maximal deformation. The potential of the technique is demonstrated and compared to air-puff imaging with Scheimpflug. Measurements ex vivo were performed on 14 freshly enucleated porcine eyes and five human donor eyes. Measurements in vivo were performed on nine human eyes. Corneal deformation was studied as a function of Intraocular Pressure (IOP, 15-45 mmHg), dehydration, changes in corneal rigidity (produced by UV corneal cross-linking, CXL), and different boundary conditions (sclera, ocular muscles). Geometrical deformation parameters were used as input for inverse finite element simulation to retrieve the corneal dynamic elastic and viscoelastic parameters. Temporal and spatial deformation profiles were very sensitive to the IOP. CXL produced a significant reduction of the cornea indentation (1.41x), and a change in the temporal symmetry of the corneal deformation profile (1.65x), indicating a change in the viscoelastic properties with treatment. Combining air-puff with dynamic imaging and finite element modeling allows characterizing the corneal biomechanics in-vivo.

SPIE Journal Paper | 10 January 2014 Open Access

Intraocular lens alignment from an en face optical coherence tomography image Purkinje-like method

Mengchan Sun, Alberto de Castro, Sergio Ortiz, Pablo Perez-Merino, Judith Birkenfeld, Susana Marcos

OE, Vol. 53, Issue 06, 061704, (January 2014) https://doi.org/10.1117/12.10.1117/1.OE.53.6.061704

KEYWORDS: Optical coherence tomography, Eye, Eye models, Image segmentation, 3D image processing, Optical alignment, Computer simulations, Cornea, Refractive index, Reflection

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Proceedings Article | 10 January 1996 Paper

Foveal cone mosaic imaged in vivo by an objective high-resolution technique

Susana Marcos, Rafael Fonolla Navarro, Pablo Artal

Proceedings Volume 2632, (1996) https://doi.org/10.1117/12.229572

KEYWORDS: Cones, Eye, Spatial frequencies, In vivo imaging, Speckle pattern, Speckle interferometry, Distance measurement, Diffraction, Retina, Image resolution

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SPIE Journal Paper | 1 March 1995

Through focus image quality of eyes implanted with monofocal and multifocal intraocular lenses

Pablo Artal, Susana Marcos, Rafael Fonolla Navarro, Ismael Miranda, Manuel Ferro

OE, Vol. 34, Issue 03, (March 1995) https://doi.org/10.1117/12.10.1117/12.191818

KEYWORDS: Image quality, Modulation transfer functions, Monochromatic aberrations, Eye, Lenses, Modulation, Intraocular lenses, Optical testing, Digital imaging, Spatial frequencies

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