Prof. Yoshinori Harada Profile

Prof. Yoshinori Harada

at Kyoto Prefectural Univ of Medicine

SPIE Involvement:

Author

Publications (20)

Proceedings Article | 13 March 2024 Presentation

Presentation

Multimodal imaging of cryofixed cells using Raman and fluorescence structured illumination microscopy

Kosuke Tsuji, Masahito Yamanaka, Yasuaki Kumamoto, Shoko Tamura, Kenta Mizushima, Kakeru Kono, Toshiki Kubo, Hanae Hirano, Kazunori Sugiura, Shun-Ichi Fukushima, Takumi Kunimoto, Kentaro Nishida, Yoshinori Harada, Nicholas Smith, Rainer Heintzmann, Takeharu Nagai, Hideo Tanaka, Katsumasa Fujita

Proceedings Volume PC12846, PC128460B (2024) https://doi.org/10.1117/12.3000361

KEYWORDS: Raman spectroscopy, Multimodal imaging, Fluorescence, Biological imaging, Optical microscopy, Light sources and illumination, Microscopes, Biological samples, Visualization, Temporal resolution

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Proceedings Article | 13 March 2024 Presentation

Presentation

High-sensitivity Raman microscopy of cryofixed biological samples

Katsumasa Fujita, Kenta Mizushima, Shoko Tamura, Masahito Yamanaka, Menglu Li, Yoshinori Harada, Nicholas Smith, Yasuaki Kumamoto, Hideo Tanaka

Proceedings Volume PC12839, PC1283908 (2024) https://doi.org/10.1117/12.3000955

KEYWORDS: Raman spectroscopy, Biological imaging, Signal to noise ratio, Raman scattering, Microscopy, Cryostats, Biological samples, Visualization, Tissues, Photobleaching

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Proceedings Article | 13 March 2024 Presentation

Presentation

On-the-fly slit-scanning confocal Raman microscope guaranteeing the accuracy of discrimination

Toshiki Kubo, Koji Tabata, Hiroyuki Kawagoe, James Nicholas Taylor, Jean-Emmanuel Clement, Yoshinori Harada, Atsuyoshi Nakamura, Katsumasa Fujita, Tamiki Komatsuzaki

Proceedings Volume PC12839, PC128390D (2024) https://doi.org/10.1117/12.3001684

KEYWORDS: Raman spectroscopy, Confocal microscopy, Biological samples, Microscopes, Polymethylmethacrylate, Cancer, Liver, Cancer detection, Adipose tissue, Tissues

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Proceedings Article | 13 March 2024 Presentation

Presentation

Raman imaging for high sensitivity detection of intracellular molecules in cryofixed biological specimens

Kenta Mizushima, Yasuaki Kumamoto, Shoko Tamura, Masahito Yamanaka, Kentaro Mochizuki, Menglu Li, Syusuke Egoshi, Kosuke Dodo, Yasunori Harada, Nicholas Smith, Mikiko Sodeoka, Hideo Tanaka, Katsumasa Fujita

Proceedings Volume PC12855, PC1285519 (2024) https://doi.org/10.1117/12.3000359

KEYWORDS: Raman spectroscopy, Biological imaging, Biological samples, Molecules, Signal to noise ratio, Molecular biology, Spatial resolution, Microscopes, Liquids, Cryogenics

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Proceedings Article | 13 March 2024 Poster

Poster

Development of information theoretic analysis to quantify information specific to Raman images

Ryoya Kondo, Yuta Mizuno, Jean-Emmanuel Clement, Kentaro Mochizuki, Katsumasa Fujita, Yoshinori Harada, Tamiki Komatsuzaki

Proceedings Volume PC12839, PC128390W (2024) https://doi.org/10.1117/12.3002493

KEYWORDS: Raman spectroscopy, Liver, Diseases and disorders, Imaging spectroscopy, Chemical analysis, Spectroscopy, Chemical species, Visualization, Tissues, Reflection

Proceedings Article | 12 March 2024 Presentation + Paper

Presentation + Paper

Fast and accurate discrimination high-speed Raman imaging combined with multi-armed bandit algorithm in reinforcement learning

Koji Tabata, Hiroyuki Kawagoe, Toshiki Kubo, James Taylor, Kentaro Mochizuki, Jean-Emmanuel Clement, Yasuaki Kumamoto, Yoshinori Harada, Atsuyoshi Nakamura, Katsumasa Fujita, Tamiki Komatsuzaki

Proceedings Volume 12853, 128530A (2024) https://doi.org/10.1117/12.3002689

KEYWORDS: Raman spectroscopy, Light sources and illumination, Machine learning, Medical research, Random forests, Microscopy, Microscopes, Engineering, Diagnostics, Decision trees

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Proceedings Article | 20 September 2023 Paper

Paper

High-speed Raman spectroscopic diagnosis guaranteeing accuracy by reinforcement learning

Toshiki Kubo, Koji Tabata, Hiroyuki Kawagoe, James Taylor, Kentaro Mochizuki, Jean-Emmanuel Clement, Yasuaki Kumamoto, Yoshinori Harada, Atsuyoshi Nakamura, Katsumasa Fujita, Tamiki Komatsuzaki

Proceedings Volume 12608, 126081A (2023) https://doi.org/10.1117/12.3007934

KEYWORDS: Raman spectroscopy, Microscopy, Machine learning, Spectroscopy, Light sources and illumination, Raman scattering, Medical research, Thyroid, Microscopes, Engineering

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Proceedings Article | 15 June 2020 Paper

Paper

High-throughput discrimination of cancerous and noncancerous human cell lines by high-speed spontaneous Raman microscopy

Yasuaki Kumamoto, Kentaro Mochizuki, Kosuke Hashimoto, Yoshinori Harada, Hideo Tanaka, Katsumasa Fujita

Proceedings Volume 11521, 1152112 (2020) https://doi.org/10.1117/12.2573223

KEYWORDS: Raman spectroscopy, Microscopy, Sensors, Signal detection, Image acquisition, Confocal microscopy, Biological research, Statistical analysis, Cancer, Raman scattering

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Proceedings Article | 17 May 2018 Paper

Paper

Photoacoustic microscopy with transmissive adaptive optics using liquid crystal

Yusuke Notsuka, Makoto Kurihara, Nobuyuki Hashimoto, Yoshinori Harada, Eiji Takahashi, Yoshihisa Yamaoka

Proceedings Volume 10685, 106853N (2018) https://doi.org/10.1117/12.2306740

KEYWORDS: Adaptive optics, Liquid crystals, Tissues, Photoacoustic microscopy, Wavefront aberrations, Visualization, Optical components, Tissue optics, Blood vessels

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Proceedings Article | 19 February 2018 Presentation + Paper

Presentation + Paper

Fast focus-scanning head in two-photon photoacoustic microscopy with electrically controlled liquid lens

Yoshihisa Yamaoka, Yuka Kimura, Yoshinori Harada, Tetsuro Takamatsu, Eiji Takahashi

Proceedings Volume 10494, 104942J (2018) https://doi.org/10.1117/12.2287391

KEYWORDS: Liquid lenses, Liquids, Photoacoustic spectroscopy, Head, Photoacoustic microscopy, Signal detection, Absorption, Signal generators, Rhodamine B, Ultrasonics

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Proceedings Article | 19 April 2017 Presentation

Presentation

Rapid and accurate peripheral nerve detection using multipoint Raman imaging (Conference Presentation)

Yasuaki Kumamoto, Takeo Minamikawa, Akinori Kawamura, Junichi Matsumura, Yuichiro Tsuda, Juichiro Ukon, Yoshinori Harada, Hideo Tanaka, Tetsuro Takamatsu

Proceedings Volume 10054, 1005405 (2017) https://doi.org/10.1117/12.2251283

KEYWORDS: Medicine, Nerve, Raman spectroscopy, Surgery, Tissues, Raman scattering, Visualization, Image visualization, Connective tissue, Biomedical optics

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Proceedings Article | 14 February 2017 Paper

Paper

Raman spectroscopic detection of peripheral nerves towards nerve-sparing surgery

Takeo Minamikawa, Yoshinori Harada, Tetsuro Takamatsu

Proceedings Volume 10054, 100541E (2017) https://doi.org/10.1117/12.2250807

KEYWORDS: Nerve, Tissues, Spectroscopy, Imaging spectroscopy, Nervous system, Sensors, Principal component analysis, Biomedical optics, Surgery, Raman spectroscopy, In vivo imaging, Medicine

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Proceedings Article | 8 February 2017 Presentation + Paper

Presentation + Paper

Simple and optimum background-free estimation method of PPIX fluorescence for 5-ALA-based fluorescence diagnosis of malignant lesions

Takeo Minamikawa, Hisataka Matsuo, Yoshiyuki Kato, Yoshinori Harada, Eigo Otsuji, Akio Yanagisawa, Hideo Tanaka, Tetsuro Takamatsu

Proceedings Volume 10047, 100470S (2017) https://doi.org/10.1117/12.2250780

KEYWORDS: Lymphatic system, Chromophores, Collagen, Tissues, Multispectral imaging, Error analysis, Cancer, Photodynamic therapy, Fluorescence spectroscopy, Colorectal cancer, Bladder cancer, Surgery, Tumors, Liver cancer

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Proceedings Article | 3 March 2014 Paper

Paper

Improvement of signal detection selectivity and efficiency in two-photon absorption-induced photoacoustic microscopy

Yoshihisa Yamaoka, Yoshinori Harada, Shigeru Nishino, Seiji Maehara, Shujiro Hamano, Tetsuro Takamatsu

Proceedings Volume 8943, 89433C (2014) https://doi.org/10.1117/12.2039323

KEYWORDS: Photoacoustic spectroscopy, Signal detection, Objectives, Transducers, Absorption, Pulsed laser operation, Signal generators, Rhodamine, Photoacoustic microscopy, Tissue optics

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Proceedings Article | 22 February 2013 Paper

Paper

Raman microspectroscopy for visualization of peripheral nerves

Takeo Minamikawa, Yoshinori Harada, Noriaki Koizumi, Tetsuro Takamatsu

Proceedings Volume 8588, 85880P (2013) https://doi.org/10.1117/12.2001015

KEYWORDS: Raman spectroscopy, Tissues, Nerve, Imaging spectroscopy, Surgery, Connective tissue, Blood vessels, Visualization, Image analysis, Statistical analysis

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Proceedings Article | 11 February 2011 Paper

Paper

Autofluorescence ratio imaging of human colonic adenomas

Katsuichi Imaizumi, Yoshinori Harada, Naoki Wakabayashi, Yoshihisa Yamaoka, Ping Dai, Hideo Tanaka, Tetsuro Takamatsu

Proceedings Volume 7902, 79020E (2011) https://doi.org/10.1117/12.874869

KEYWORDS: Luminescence, Tumors, Endoscopy, Visualization, Bandpass filters, Reflectivity, Imaging systems, Diagnostics, CCD cameras, Medicine

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Proceedings Article | 23 February 2009 Paper

Paper

Tissue imaging of myocardial infarct regions by a slit-scanning Raman microscope

Mitsugu Ogawa, Yoshinori Harada, Yoshihisa Yamaoka, Katsumasa Fujita, Tetsuro Takamatsu

Proceedings Volume 7169, 71690H (2009) https://doi.org/10.1117/12.808079

KEYWORDS: Raman spectroscopy, Tissues, Heart, Collagen, Microscopes, Confocal microscopy, Tissue optics, Curium, Principal component analysis, Imaging systems

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Proceedings Article | 21 February 2009 Paper

Paper

Detection of disseminated peritoneal tumors by fluorescein diacrylate in mice

Yoshinori Harada, Hirokazu Furuta, Yasutoshi Murayama, Ping Dai, Yuta Fujikawa, Yasuteru Urano, Tetsuo Nagano, Koki Morishita, Akira Hasegawa, Tetsuro Takamatsu

Proceedings Volume 7190, 719019 (2009) https://doi.org/10.1117/12.809063

KEYWORDS: Tumors, Luminescence, Cancer, Mouse models, Colorectal cancer, Cell biology, Fluorescence spectroscopy, Tissues, Medicine, In vivo imaging

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Proceedings Article | 8 February 2008 Paper

Paper

Imaging of anticancer agent distribution by a slit-scanning Raman microscope

Yoshinori Harada, Taisuke Ota, Dai Ping, Yoshihisa Yamaoka, Keisaku Hamada, Katsumasa Fujita, Tetsuro Takamatsu

Proceedings Volume 6853, 685308 (2008) https://doi.org/10.1117/12.763078

KEYWORDS: Raman spectroscopy, Microscopes, Confocal microscopy, Raman scattering, Image acquisition, Light scattering, Microscopy, Molecules, Biomedical optics, Molecular lasers

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Proceedings Article | 8 February 2008 Paper

Paper

Mucosal layer as major source of green autofluorescence in the colon under excitation by blue light

Keimei Nakano, Yoshinori Harada, Yoshihisa Yamaoka, Kiichiro Miyawaki, Naoki Wakabayashi, Shoji Mitsufuji, Katsuichi Imaizumi, Hideyuki Takaoka, Masaya Nakaoka, Tetsuro Takamatsu

Proceedings Volume 6853, 68531H (2008) https://doi.org/10.1117/12.763245

KEYWORDS: Colon, Luminescence, Tissues, Light, Tumors, Femtosecond phenomena, Lamps, Microscopes, Ultraviolet radiation, Photons

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Showing 5 of 20 publications

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