Ms. Amber M. Arquitola Profile

Amber M. Arquitola

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Publications (3)

Proceedings Article | 13 June 2023 Poster + Paper

Investigation of recombination mechanisms in GaAsSb photodiodes using minority carrier lifetime measurements

Amber Arquitola, Neha Nooman, Seunghyun Lee, Hyemin Jung, Sanjay Krishna

Proceedings Volume 12534, 125341Z (2023) https://doi.org/10.1117/12.2663859

KEYWORDS: Carrier dynamics, Infrared materials, Material characterization, Semiconductor materials, Temperature metrology, Doping, Dark current, Short wave infrared radiation, Photodiodes, Avalanche photodetectors, Reflectivity, Microwave radiation

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Proceedings Article | 29 August 2017 Presentation + Paper

Multimodal ophthalmic imaging using spectrally encoded scanning laser ophthalmoscopy and optical coherence tomography

Mohamed El-Haddad, Joseph Malone, Jianwei Li, Ivan Bozic, Amber Arquitola, Karen Joos, Shriji Patel, Yuankai Tao

Proceedings Volume 10352, 1035209 (2017) https://doi.org/10.1117/12.2275552

KEYWORDS: Optical coherence tomography, Scanning laser ophthalmoscopy, Ophthalmic imaging, In vivo imaging, Signal detection, Multimodal imaging, Scanners, Imaging systems, Optical scanning systems, Optical tracking

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Ophthalmic surgery involves manipulation of delicate, layered tissue structures on milli- to micrometer scales. Traditional surgical microscopes provide an inherently two-dimensional view of the surgical field with limited depth perception which precludes accurate depth-resolved visualization of these tissue layers, and limits the development of novel surgical techniques. We demonstrate multimodal swept-source spectrally encoded scanning laser ophthalmoscopy and optical coherence tomography (SS-SESLO-OCT) to address current limitations of image-guided ophthalmic microsurgery. SS-SESLO-OCT provides inherently co-registered en face and cross-sectional field-of-views (FOVs) at a line rate of 400 kHz and >2 GPix/s throughput. We show in vivo imaging of the anterior segment and retinal fundus of a healthy volunteer, and preliminary results of multi-volumetric mosaicking for ultrawide-field retinal imaging with 90° FOV. Additionally, a scan-head was rapid-prototyped with a modular architecture which enabled integration of SS-SESLO-OCT with traditional surgical microscope and slit-lamp imaging optics. Ex vivo surgical maneuvers were simulated in cadaveric porcine eyes. The system throughput enabled volumetric acquisition at 10 volumes-per-second (vps) and allowed visualization of surgical dynamics in corneal sweeps, compressions, and dissections, and retinal sweeps, compressions, and elevations. SESLO en face images enabled simple real-time co-registration with the surgical microscope FOV, and OCT cross-sections provided depth-resolved visualization of instrument-tissue interactions. Finally, we demonstrate novel augmented-reality integration with the surgical view using segmentation overlays to aid surgical guidance. SS-SESLO-OCT may benefit clinical diagnostics by enabling aiming, registration, and mosaicking; and intraoperative imaging by allowing for real-time surgical feedback, instrument tracking, and overlays of computationally extracted biomarkers of disease.

Proceedings Article | 17 February 2017 Presentation + Paper

Image-guided feedback for ophthalmic microsurgery using multimodal intraoperative swept-source spectrally encoded scanning laser ophthalmoscopy and optical coherence tomography

Jianwei Li, Joseph Malone, Mohamed El-Haddad, Amber Arquitola, Karen Joos, Shriji Patel, Yuankai Tao

Proceedings Volume 10053, 100530I (2017) https://doi.org/10.1117/12.2254847

KEYWORDS: Optical coherence tomography, Visualization, Scanning laser ophthalmoscopy, Tissues, In vivo imaging, Microsurgery, Ophthalmic imaging, Microscopes, Multimodal imaging, Eye, Image segmentation, Surgery

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Surgical interventions for ocular diseases involve manipulations of semi-transparent structures in the eye, but limited visualization of these tissue layers remains a critical barrier to developing novel surgical techniques and improving clinical outcomes. We addressed limitations in image-guided ophthalmic microsurgery by using microscope-integrated multimodal intraoperative swept-source spectrally encoded scanning laser ophthalmoscopy and optical coherence tomography (iSS-SESLO-OCT). We previously demonstrated in vivo human ophthalmic imaging using SS-SESLO-OCT, which enabled simultaneous acquisition of en face SESLO images with every OCT cross-section. Here, we integrated our new 400 kHz iSS-SESLO-OCT, which used a buffered Axsun 1060 nm swept-source, with a surgical microscope and TrueVision stereoscopic viewing system to provide image-based feedback. In vivo human imaging performance was demonstrated on a healthy volunteer, and simulated surgical maneuvers were performed in ex vivo porcine eyes. Denselysampled static volumes and volumes subsampled at 10 volumes-per-second were used to visualize tissue deformations and surgical dynamics during corneal sweeps, compressions, and dissections, and retinal sweeps, compressions, and elevations. En face SESLO images enabled orientation and co-registration with the widefield surgical microscope view while OCT imaging enabled depth-resolved visualization of surgical instrument positions relative to anatomic structures-of-interest. TrueVision heads-up display allowed for side-by-side viewing of the surgical field with SESLO and OCT previews for real-time feedback, and we demonstrated novel integrated segmentation overlays for augmented-reality surgical guidance. Integration of these complementary imaging modalities may benefit surgical outcomes by enabling real-time intraoperative visualization of surgical plans, instrument positions, tissue deformations, and image-based surrogate biomarkers correlated with completion of surgical goals.

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