Dr. Jianwei David Li Profile

Dr. Jianwei David Li

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Publications (12)

Proceedings Article | 13 March 2024 Presentation

Line-scan phase-resolved synthetic wavelength LiDAR using an off-axis holographic approach

Jingkai Zhang, Joseph Izatt, Robert Trout, Jianwei Li, Julia Foust, Al-Hafeez Dhalla, Kevin Zhou

Proceedings Volume PC12830, PC128300E (2024) https://doi.org/10.1117/12.3002644

KEYWORDS: Holography, Line scan image sensors, LIDAR, Optical coherence, 3D image processing, Interferograms, Imaging technologies, Imaging systems, Coherence imaging, Switches

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Proceedings Article | 13 March 2024 Presentation

Optimal focusing for long-range OCT: not necessarily on the sample

Julia Foust, Robert Trout, Jingkai Zhang, Jianwei Li, Al-Hafeez Dhalla, Joseph Izatt

Proceedings Volume PC12830, PC128301X (2024) https://doi.org/10.1117/12.3003551

KEYWORDS: Optical coherence tomography, Signal detection, Reflectivity, Gaussian beams, Objectives, Detection theory, Signal intensity, Robot vision, Medical imaging, Plane waves

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Proceedings Article | 13 March 2024 Presentation

Synthetic data algorithm development for high-speed instrument tracking of OCT imaging during anterior chamber ophthalmic surgeries

Harvey Shi, Pablo Ortiz, Jianwei Li, Amit Narawane, Robert Trout, Yuan Tian, Mark Draelos, Ryan McNabb, Anthony Kuo, Joseph Izatt

Proceedings Volume PC12824, PC1282415 (2024) https://doi.org/10.1117/12.2692376

KEYWORDS: Algorithm development, Microscopes, Equipment, Instrument modeling, Eye models, Vacuum chambers, 3D modeling, Optical coherence tomography, Education and training, Surgery

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Proceedings Article | 17 March 2023 Presentation

Real-time feature-guided image fusion of posterior-segment intrasurgical optical coherence tomography and digital surgical microscopy

Robert Trout, Christian Viehland, Jianwei Li, William Raynor, Al-Hafeez Dhalla, Anthony Kuo, Lejla Vajzovic, Cynthia Toth, Joseph Izatt

Proceedings Volume PC12360, PC123600H (2023) https://doi.org/10.1117/12.2650678

KEYWORDS: Surgery, Optical coherence tomography, Microscopy, Visualization, Image fusion, Eye, Image-guided intervention, Coherence imaging, Microscopes, Feature extraction

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Proceedings Article | 7 March 2022 Presentation

Intraoperative optical coherence tomography with 4D visualization of surgical maneuvers and quantitative measurements of intraocular structures

Jianwei Li, Christian Viehland, Al-Hafeez Dhalla, William Raynor, Robert Trout, Anthony Kuo, Cynthia Toth, Lejla Vajzovic, Joseph Izatt

Proceedings Volume PC11941, PC119410S (2022) https://doi.org/10.1117/12.2608834

KEYWORDS: Optical coherence tomography, Visualization, Surgery, Microscopes, Scanners, Ophthalmology, Gold, Genetics, 3D visualizations, Microsurgery

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Proceedings Article | 7 March 2022 Presentation

Feature-guided image fusion of intrasurgical optical coherence tomography and digital surgical microscopy

Robert Trout, Jianwei Li, Christian Viehland, William Raynor, Al-Hafeez Dhalla, Anthony Kuo, Lejla Vajzovic, Cynthia Toth, Joseph Izatt

Proceedings Volume PC11941, PC119410B (2022) https://doi.org/10.1117/12.2607420

KEYWORDS: Surgery, Optical coherence tomography, Microscopy, Visualization, Image fusion, Eye, Image-guided intervention, Coherence imaging, Video microscopy, Video

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Proceedings Article | 9 March 2020 Presentation

Real time volumetric intrasurgical optical coherence tomography with 4D visualization of surgical maneuvers (Conference Presentation)

Christian Viehland, Al-Hafeez Dhalla, Jianwei Li, Moseph Jackson-Atogi, Lejla Vajzovic, Anthony Kuo, Cynthia Toth, Joseph Izatt

Proceedings Volume 11218, 112180K (2020) https://doi.org/10.1117/12.2550063

KEYWORDS: Optical coherence tomography, Visualization, Imaging systems, Surgery, Microscopes, Retina, System integration, Tissues, Cornea, Retinal scanning

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Proceedings Article | 9 March 2020 Presentation

Quantitative measurements of intraocular structures including subretinal microinjection bleb volumes using intraoperative optical coherence tomography (Conference Presentation)

Jianwei Li, William Raynor, Ananth Sastry, Al-Hafeez Dhalla, Cynthia Toth, Christian Viehland, Lejla Vajzovic, Joseph Izatt

Proceedings Volume 11228, 112280H (2020) https://doi.org/10.1117/12.2546504

KEYWORDS: Optical coherence tomography, Eye models, Surgery, Imaging systems, Visualization, Eye, Therapeutics, Image analysis, Optical spheres

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Proceedings Article | 13 March 2019 Presentation

Constant linear velocity spiral scanning for real time 4D OCT with visualization in virtual reality (Conference Presentation)

Jianwei Li, Oscar Carrasco-Zevallos, Moseph Jackson-Atogi, Mark Draelos, Christian Viehland, Brenton Keller, Ryan McNabb, Anthony Kuo, Joseph Izatt

Proceedings Volume 10858, 108580D (2019) https://doi.org/10.1117/12.2510352

KEYWORDS: Optical coherence tomography, Visualization, Virtual reality, Scanners, Raster graphics, Data acquisition, Retina, Surgery

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Proceedings Article | 29 August 2017 Presentation + Paper

Multimodal ophthalmic imaging using spectrally encoded scanning laser ophthalmoscopy and optical coherence tomography

Mohamed El-Haddad, Joseph Malone, Jianwei Li, Ivan Bozic, Amber Arquitola, Karen Joos, Shriji Patel, Yuankai Tao

Proceedings Volume 10352, 1035209 (2017) https://doi.org/10.1117/12.2275552

KEYWORDS: Optical coherence tomography, Scanning laser ophthalmoscopy, Ophthalmic imaging, In vivo imaging, Signal detection, Multimodal imaging, Scanners, Imaging systems, Optical scanning systems, Optical tracking

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Ophthalmic surgery involves manipulation of delicate, layered tissue structures on milli- to micrometer scales. Traditional surgical microscopes provide an inherently two-dimensional view of the surgical field with limited depth perception which precludes accurate depth-resolved visualization of these tissue layers, and limits the development of novel surgical techniques. We demonstrate multimodal swept-source spectrally encoded scanning laser ophthalmoscopy and optical coherence tomography (SS-SESLO-OCT) to address current limitations of image-guided ophthalmic microsurgery. SS-SESLO-OCT provides inherently co-registered en face and cross-sectional field-of-views (FOVs) at a line rate of 400 kHz and >2 GPix/s throughput. We show in vivo imaging of the anterior segment and retinal fundus of a healthy volunteer, and preliminary results of multi-volumetric mosaicking for ultrawide-field retinal imaging with 90° FOV. Additionally, a scan-head was rapid-prototyped with a modular architecture which enabled integration of SS-SESLO-OCT with traditional surgical microscope and slit-lamp imaging optics. Ex vivo surgical maneuvers were simulated in cadaveric porcine eyes. The system throughput enabled volumetric acquisition at 10 volumes-per-second (vps) and allowed visualization of surgical dynamics in corneal sweeps, compressions, and dissections, and retinal sweeps, compressions, and elevations. SESLO en face images enabled simple real-time co-registration with the surgical microscope FOV, and OCT cross-sections provided depth-resolved visualization of instrument-tissue interactions. Finally, we demonstrate novel augmented-reality integration with the surgical view using segmentation overlays to aid surgical guidance. SS-SESLO-OCT may benefit clinical diagnostics by enabling aiming, registration, and mosaicking; and intraoperative imaging by allowing for real-time surgical feedback, instrument tracking, and overlays of computationally extracted biomarkers of disease.

Proceedings Article | 17 February 2017 Presentation + Paper

Image-guided feedback for ophthalmic microsurgery using multimodal intraoperative swept-source spectrally encoded scanning laser ophthalmoscopy and optical coherence tomography

Jianwei Li, Joseph Malone, Mohamed El-Haddad, Amber Arquitola, Karen Joos, Shriji Patel, Yuankai Tao

Proceedings Volume 10053, 100530I (2017) https://doi.org/10.1117/12.2254847

KEYWORDS: Optical coherence tomography, Visualization, Scanning laser ophthalmoscopy, Tissues, In vivo imaging, Microsurgery, Ophthalmic imaging, Microscopes, Multimodal imaging, Eye, Image segmentation, Surgery

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Surgical interventions for ocular diseases involve manipulations of semi-transparent structures in the eye, but limited visualization of these tissue layers remains a critical barrier to developing novel surgical techniques and improving clinical outcomes. We addressed limitations in image-guided ophthalmic microsurgery by using microscope-integrated multimodal intraoperative swept-source spectrally encoded scanning laser ophthalmoscopy and optical coherence tomography (iSS-SESLO-OCT). We previously demonstrated in vivo human ophthalmic imaging using SS-SESLO-OCT, which enabled simultaneous acquisition of en face SESLO images with every OCT cross-section. Here, we integrated our new 400 kHz iSS-SESLO-OCT, which used a buffered Axsun 1060 nm swept-source, with a surgical microscope and TrueVision stereoscopic viewing system to provide image-based feedback. In vivo human imaging performance was demonstrated on a healthy volunteer, and simulated surgical maneuvers were performed in ex vivo porcine eyes. Denselysampled static volumes and volumes subsampled at 10 volumes-per-second were used to visualize tissue deformations and surgical dynamics during corneal sweeps, compressions, and dissections, and retinal sweeps, compressions, and elevations. En face SESLO images enabled orientation and co-registration with the widefield surgical microscope view while OCT imaging enabled depth-resolved visualization of surgical instrument positions relative to anatomic structures-of-interest. TrueVision heads-up display allowed for side-by-side viewing of the surgical field with SESLO and OCT previews for real-time feedback, and we demonstrated novel integrated segmentation overlays for augmented-reality surgical guidance. Integration of these complementary imaging modalities may benefit surgical outcomes by enabling real-time intraoperative visualization of surgical plans, instrument positions, tissue deformations, and image-based surrogate biomarkers correlated with completion of surgical goals.

Proceedings Article | 8 February 2017 Presentation + Paper

Modular multimodal swept-source spectrally encoded scanning laser ophthalmoscopy and optical coherence tomography scan-head for surgical microscope-integrated and slit-lamp imaging

Joseph Malone, Jianwei Li, Mohamed El-Haddad, Karen Joos, Shriji Patel, Yuankai Tao

Proceedings Volume 10045, 100451D (2017) https://doi.org/10.1117/12.2252315

KEYWORDS: Optical coherence tomography, Scanning laser ophthalmoscopy, Ophthalmic imaging, Multimodal imaging, In vivo imaging, Imaging systems, Relays, Non-invasive medical diagnostics, Visualization, Fiber couplers, Microscopes, Mirrors, Computer aided design

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