Dr. Ann M. Gillenwater Profile

Dr. Ann M. Gillenwater

Associate Professor, Head & Neck Surgery at Univ Texas MD Anderson Cancer Ctr

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Author

Publications (28)

Proceedings Article | 21 October 2024 Poster

A deep learning mucosal segmentation algorithm for a mobile detection of oral cancer (mDOC) platform

Mengyuan Xue, Ruchika Mitbander, Jennifer Carns, Richard Schwarz, Nadarajah Vigneswaran, Ann Gillenwater, Rebecca Richards-Kortum

Proceedings Volume 13186, 1318612 (2024) https://doi.org/10.1117/12.3034638

KEYWORDS: Image segmentation, Cancer, Detection and tracking algorithms, Cancer detection, Deep learning, Algorithm development, Education and training, Network architectures, Image classification, Autofluorescence

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Proceedings Article | 21 October 2024 Poster

Optimization of stains for slide-free histopathology of head and neck tumors using deep-learning, depth-of-field microscope

Bakai Sheyitov, Cheima Hicheri, Kushal Vyas, Lingbo Jin, Yubo Tang, Pavel Tsitovich, Michelle Williams, Ann Gillenwater, Konstantin Sokolov, Ashok Veeraraghavan, Rebecca Richards-Kortum

Proceedings Volume 13186, 131861A (2024) https://doi.org/10.1117/12.3034727

KEYWORDS: Tumors, Neck, Head, Microscopes, Histopathology, Depth of field, Tissues, Resection, Fluorescence, Dyes

SPIE Journal Paper | 21 May 2024 Open Access

Use of topical methylene blue to image nuclear morphometry with a low-cost scanning darkfield microendoscope

Huayu Hou, Jennifer Carns, Richard A. Schwarz, Ann M. Gillenwater, Sharmila Anandasabapathy, Rebecca R. Richards-Kortum

JBO, Vol. 29, Issue 05, 050501, (May 2024) https://doi.org/10.1117/12.10.1117/1.JBO.29.5.050501

KEYWORDS: Imaging systems, Image quality, Fluorescence imaging, Tissues, Light sources and illumination, In vivo imaging, Reflectivity, Cancer detection, Fiber optics, Biomedical applications

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SPIE Journal Paper | 13 January 2023 Open Access

Multimodal optical imaging with real-time projection of cancer risk and biopsy guidance maps for early oral cancer diagnosis and treatment

Jackson Coole, David Brenes, Ruchika Mitbander, Imran Vohra, Huayu Hou, Alex Kortum, Yubo Tang, Yajur Maker, Richard Schwarz, Jennifer Carns, Hawraa Badaoui, Michelle Williams, Nadarajah Vigneswaran, Ann Gillenwater, Rebecca Richards-Kortum

JBO, Vol. 28, Issue 01, 016002, (January 2023) https://doi.org/10.1117/12.10.1117/1.JBO.28.1.016002

KEYWORDS: Biopsy, Cancer, Microscopes, Multimodal imaging, Optical imaging, Imaging systems, Cameras, Tongue, Projection systems, Biomedical optics

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SPIE Journal Paper | 21 September 2020 Open Access

Algorithm to quantify nuclear features and confidence intervals for classification of oral neoplasia from high-resolution optical images

Eric Yang, David Brenes, Imran Vohra, Richard Schwarz, Michelle Williams, Nadarajah Vigneswaran, Ann Gillenwater, Rebecca Richards-Kortum

JMI, Vol. 7, Issue 05, 054502, (September 2020) https://doi.org/10.1117/12.10.1117/1.JMI.7.5.054502

KEYWORDS: Neodymium, Algorithm development, Tissues, Image classification, Diagnostics, Biopsy, Image segmentation, Cancer, Visualization, Convolution

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SPIE Journal Paper | 21 February 2019 Open Access

Development of an integrated multimodal optical imaging system with real-time image analysis for the evaluation of oral premalignant lesions

Eric Yang, Imran Vohra, Hawraa Badaoui, Richard Schwarz, Katelin Cherry, Timothy Quang, Justin Jacob, Alex Lang, Nancy Bass, Jessica Rodriguez, Michelle Williams, Nadarajah Vigneswaran, Ann Gillenwater, Rebecca Richards-Kortum

JBO, Vol. 24, Issue 02, 025003, (February 2019) https://doi.org/10.1117/12.10.1117/1.JBO.24.2.025003

KEYWORDS: Brain-machine interfaces, Biopsy, Roentgenium, Image registration, Optical imaging, Imaging systems, Cancer, Image analysis, Image processing, Multimodal imaging

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Proceedings Article | 27 April 2016 Presentation

Intraoperative detection and elimination of microscopic tumors in head and neck (Conference Presentation)

Ekaterina Lukianova-Hleb, Yoo-Shin Kim, Ihar Belatsarkouski, Ehab Hanna, Ann Gillenwater, Brian O'Neill, Dmitri Lapotko

Proceedings Volume 9689, 96891Y (2016) https://doi.org/10.1117/12.2217942

KEYWORDS: Tumors, Head, Neck, Cancer, Surgery, Tissues, Standards development, Plasmonics, Nanotechnology, Target detection

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SPIE Journal Paper | 28 April 2015 Open Access

Automated frame selection process for high-resolution microendoscopy

Ayumu Ishijima, Richard Schwarz, Dongsuk Shin, Sharon Mondrik, Nadarajah Vigneswaran, Ann Gillenwater, Sharmila Anandasabapathy, Rebecca Richards-Kortum

JBO, Vol. 20, Issue 04, 046014, (April 2015) https://doi.org/10.1117/12.10.1117/1.JBO.20.4.046014

KEYWORDS: Video, Cancer, Algorithm development, Image analysis, Point-of-care devices, Image classification, Image quality, Detection and tracking algorithms, Diagnostics, In vivo imaging

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Proceedings Article | 19 May 2014 Paper

Automated frame selection process for analyzing high resolution microendoscope images

Ayumu Ishijima, Sharon Mondrik, Richard Schwarz, Nadarajah Vigneswaran, Ann Gillenwater, Rebecca Richards-Kortum

Proceedings Volume 9155, 91551M (2014) https://doi.org/10.1117/12.2062586

KEYWORDS: Image resolution, Video, Point-of-care devices, Image analysis, Cancer, Algorithm development, Image processing, Tissues, Biological research, Sensors

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Proceedings Article | 4 March 2014 Paper

Plasmonic nanobubble theranostics for intra-operative and preventive treatment of head and neck squamous cell carcinoma

Ekaterina Lukianova-Hleb, Xiaoyang Ren, Rupa Sawant, Ann Gillenwater, Michael Kupferman, Ehab Hanna, Joseph Zasadzinski, Xiangwei Wu, Vladimir Torchilin, Dmitri Lapotko

Proceedings Volume 8926, 89262D (2014) https://doi.org/10.1117/12.2038277

KEYWORDS: Plasmonics, Cancer, Tumors, Laser therapeutics, Nanotechnology, X-rays, Surgery, Head, Neck, Gold

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SPIE Journal Paper | 20 December 2013 Open Access

Vital-dye-enhanced multimodal imaging of neoplastic progression in a mouse model of oral carcinogenesis

Anne Hellebust, Kelsey Rosbach, Jessica Keren Wu, Jennifer Nguyen, Ann Gillenwater, Nadarajah Vigneswaran, Rebecca Richards-Kortum

JBO, Vol. 18, Issue 12, 126017, (December 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.12.126017

KEYWORDS: Luminescence, Tissues, Cancer, Pathology, Confocal microscopy, Tongue, Tumor growth modeling, Multimodal imaging, Optical imaging, Natural surfaces

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Proceedings Article | 9 February 2012 Paper

Longitudinal evaluation of patients with oral potentially malignant disorders using optical imaging and spectroscopy

Richard Schwarz, Mark Pierce, Sharon Mondrik, Wen Gao, Mary Quinn, Vijayashree Bhattar, Michelle Williams, Nadarajah Vigneswaran, Ann Gillenwater, Rebecca Richards-Kortum

Proceedings Volume 8207, 82071J (2012) https://doi.org/10.1117/12.921162

KEYWORDS: Imaging spectroscopy, Spectroscopy, Tongue, Tissue optics, Cancer, Auto-fluorescence imaging, Surgery, Optical spectroscopy, Biopsy, Optical imaging

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Proceedings Article | 18 February 2011 Paper

Real-time spectroscopic evaluation of oral lesions and comparisons with histopathology

Richard Schwarz, Wen Gao, Jennifer Nguyen, Nadarajah Vigneswaran, Karen Adler-Storthz, Vijayashree Bhattar, Michelle Williams, Ann Gillenwater, Rebecca Richards-Kortum

Proceedings Volume 7883, 78832K (2011) https://doi.org/10.1117/12.887758

KEYWORDS: Imaging spectroscopy, Spectroscopy, Tissue optics, Optical testing, Pathology, Diagnostics, Biopsy, Tissues, Optical spectroscopy, Cancer

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Proceedings Article | 18 February 2011 Paper

Oral cancer screening approach based on labeling exfoliated oral cells with molecularly-targeted optical contrast agents

Veronica Leautaud, Charles Horres, Vijayashree Bhattar, Michelle Williams, Ann Gillenwater, Rebecca Richards-Kortum

Proceedings Volume 7883, 78832H (2011) https://doi.org/10.1117/12.887755

KEYWORDS: Biopsy, Cancer, Magnetism, Luminescence, Confocal microscopy, Gold, Microscopes, Nanoparticles, Head, Neck

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SPIE Journal Paper | 1 November 2010 Open Access

Comparison of multispectral wide-field optical imaging modalities to maximize image contrast for objective discrimination of oral neoplasia

Darren Roblyer, Cristina Kurachi, Vanda Stepanek, Richard Schwarz, Michelle Williams, Adel El-Naggar, J. Jack Lee, Ann Gillenwater, Rebecca Richards-Kortum

JBO, Vol. 15, Issue 06, 066017, (November 2010) https://doi.org/10.1117/12.10.1117/1.3516593

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Proceedings Article | 2 March 2010 Paper

Wide-field and high-resolution optical imaging for early detection of oral neoplasia

Mark Pierce, Richard Schwarz, Kelsey Rosbach, Darren Roblyer, Tim Muldoon, Michelle Williams, Adel El-Naggar, Ann Gillenwater, Rebecca Richards-Kortum

Proceedings Volume 7548, 75481U (2010) https://doi.org/10.1117/12.848347

KEYWORDS: Imaging systems, Cancer, Optical imaging, Tissue optics, Luminescence, Diagnostics, Visualization, In vivo imaging, Reflectivity, Microscopes

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Proceedings Article | 24 February 2010 Paper

Low-cost, portable imaging systems for cancer detection

Mark Pierce, Richard Schwarz, Dong-Suk Shin, Darren Roblyer, Tim Muldoon, Mohammed Rahman, Ann Gillenwater, Sharmila Anandasabapathy, Rebecca Richards-Kortum

Proceedings Volume 7556, 755606 (2010) https://doi.org/10.1117/12.848553

KEYWORDS: Cancer, Imaging systems, Cervical cancer, Prototyping, In vivo imaging, Optical diagnostics, Optical imaging, Luminescence, Visualization, Confocal microscopy

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SPIE Journal Paper | 1 January 2010 Open Access

Efficient mucosal delivery of optical contrast agents using imidazole-modified chitosan

Bilal Ghosn, Anne van de Ven, Justina Tam, Ann Gillenwater, Konstantin Sokolov, Rebecca Richards-Kortum, Krishnendu Roy

JBO, Vol. 15, Issue 01, 015003, (January 2010) https://doi.org/10.1117/12.10.1117/1.3309739

KEYWORDS: Tissues, Nanoparticles, Macromolecules, Tissue optics, Luminescence, Biopsy, Natural surfaces, Bladder, Cancer, Confocal microscopy

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Proceedings Article | 23 February 2009 Paper

In vivo fluorescence hyperspectral imaging of oral neoplasia

Darren Roblyer, Cristina Kurachi, Ann Gillenwater, Rebecca Richards-Kortum

Proceedings Volume 7169, 71690J (2009) https://doi.org/10.1117/12.807226

KEYWORDS: Luminescence, Hyperspectral imaging, Tissues, In vivo imaging, Imaging systems, Lamps, Hyperspectral systems, Tissue optics, Spectroscopy, Calibration

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SPIE Journal Paper | 1 January 2009 Open Access

Fluorescence spectroscopy of oral tissue: Monte Carlo modeling with site-specific tissue properties

Ina Pavlova, Crystal Weber, Richard Schwarz, Michelle Williams, Ann Gillenwater, Rebecca Richards-Kortum

JBO, Vol. 14, Issue 01, 014009, (January 2009) https://doi.org/10.1117/12.10.1117/1.3065544

KEYWORDS: Luminescence, Monte Carlo methods, Tissue optics, Tissues, Photons, Cancer, Confocal microscopy, Tongue, Fluorescence spectroscopy, Tumor growth modeling

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SPIE Journal Paper | 1 November 2008 Open Access

Monte Carlo model to describe depth selective fluorescence spectra of epithelial tissue: applications for diagnosis of oral precancer

Ina Pavlova, Crystal Redden Weber, Richard Schwarz, Michelle Williams, Adel El-Naggar, Ann Gillenwater, Rebecca Richards-Kortum

JBO, Vol. 13, Issue 06, 064012, (November 2008) https://doi.org/10.1117/12.10.1117/1.3006066

KEYWORDS: Luminescence, Monte Carlo methods, Photons, Tissue optics, Tissues, Scattering, Signal detection, Absorption, Fluorescence spectroscopy, Optical properties

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SPIE Journal Paper | 1 May 2008 Open Access

Low-cost, multimodal, portable screening system for early detection of oral cancer

Mohammed Rahman, Pankaj Chaturvedi, Anne Gillenwater, Rebecca Richards-Kortum

JBO, Vol. 13, Issue 03, 030502, (May 2008) https://doi.org/10.1117/12.10.1117/1.2907455

KEYWORDS: Cancer, Luminescence, Imaging systems, Tissues, Reflectivity, Headlamps, Light emitting diodes, Cameras, Visualization, Surgery

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SPIE Journal Paper | 1 March 2008 Open Access

Probing local tissue changes in the oral cavity for early detection of cancer using oblique polarized reflectance spectroscopy: a pilot clinical trial

Linda Nieman, Chih-Wen Kan, Anne Gillenwater, Mia Markey, Konstantin Sokolov

JBO, Vol. 13, Issue 02, 024011, (March 2008) https://doi.org/10.1117/12.10.1117/1.2907450

KEYWORDS: Tissues, Tissue optics, Cancer, Diagnostics, Clinical trials, Polarization, Scattering, Tumor growth modeling, Reflectance spectroscopy, Visualization

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SPIE Journal Paper | 1 March 2008 Open Access

Multispectral optical imaging device for in vivo detection of oral neoplasia

Darren Roblyer, Rebecca Richards-Kortum, Konstantin Sokolov, Adel El-Naggar, Michelle Williams, Christine Kurachi, Anne Gillenwater

JBO, Vol. 13, Issue 02, 024019, (March 2008) https://doi.org/10.1117/12.10.1117/1.2904658

KEYWORDS: Luminescence, Tissues, Cancer, Tissue optics, Reflectivity, Optical imaging, In vivo imaging, Multispectral imaging, Imaging devices, Polarization

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Proceedings Article | 11 July 2007 Paper

Computational analysis of light scattering from collagen fiber networks

Dizem Arifler, Ina Pavlova, Ann Gillenwater, Rebecca Richards-Kortum

Proceedings Volume 6628, 66280X (2007) https://doi.org/10.1117/12.728286

KEYWORDS: Collagen, Scattering, Light scattering, Finite-difference time-domain method, 3D modeling, Tissues, Tissue optics, Confocal microscopy, Biopsy, Diagnostics

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SPIE Journal Paper | 1 November 2004 Open Access

Detection and diagnosis of oral neoplasia with an optical coherence microscope

Anne Clark, Ann Gillenwater, R. Alizadeh-Naderi, Ayman Elnaggar, Rebecca Richards-Kortum

JBO, Vol. 9, Issue 06, (November 2004) https://doi.org/10.1117/12.10.1117/1.1805558

KEYWORDS: Scattering, Confocal microscopy, Biopsy, Tissues, Tissue optics, Microscopes, Natural surfaces, Optical coherence tomography, Light scattering, Reflectivity

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Proceedings Article | 23 December 2002 Paper

Miniature injection-molded optics for fiber optic in vivo confocal microscopy

Matthew Chidley, Chen Liang, Michael Descour, Kung-Bin Sung, Rebecca Richards-Kortum, Ann Gillenwater

Proceedings Volume 4832, (2002) https://doi.org/10.1117/12.486426

KEYWORDS: Objectives, Confocal microscopy, In vivo imaging, Optics manufacturing, Fiber optics, Algorithm development, Imaging systems, Endoscopy, Optical design, Tolerancing

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Proceedings Article | 2 July 2001 Paper

Cancer screening through the use of enhanced visual systems

Urs Utzinger, Michael Bueeler, Douglas Heintzelman, Ann Gillenwater, Rebecca Richards-Kortum

Proceedings Volume 4259, (2001) https://doi.org/10.1117/12.432496

KEYWORDS: Cancer, Tissue optics, Visualization, Visual system, Luminescence, Reflectivity, Biomedical engineering, Medicine, Oncology, Spectroscopy

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Showing 5 of 28 publications

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