Dr. Dirk Grosenick Profile

Dr. Dirk Grosenick

Head of Working Group at Physikalisch-Technische Bundesanstalt (PTB)

SPIE Involvement:

Author

Publications (44)

Proceedings Article | 9 August 2023 Paper

Accuracy of tissue oxygen saturation measurement with multidistance CW fNIRS: a phantom study

Leila Motamed Jahromi, Lin Yang, Dirk Grosenick, Alexander von Lühmann

Proceedings Volume 12628, 126282D (2023) https://doi.org/10.1117/12.2670875

KEYWORDS: Oxygen, Absorption, Tissues, Scattering, Brain tissue, Attenuation, Near infrared spectroscopy, Optical properties, Near infrared, Light emitting diodes

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Proceedings Article | 9 August 2023 Paper

Short and long-term photostability of 3D printed fluorescent phantoms for near-infrared diffuse optical imaging

Sandra Schädel-Ebner, Ole Hirsch, Thomas Gladytz, Dirk Gutkelch, Kai Licha, Jörn Berger, Dirk Grosenick

Proceedings Volume 12628, 126281A (2023) https://doi.org/10.1117/12.2670658

KEYWORDS: 3D printing, Diffuse optical imaging, 3D image processing, Fluorescence, Dyes, Printing, Materials properties, Imaging systems, Fluorescence imaging, Diseases and disorders

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SPIE Journal Paper | 16 June 2022 Open Access

3D-printed tissue-simulating phantoms for near-infrared fluorescence imaging of rheumatoid diseases

Sandra Schädel-Ebner, Ole Hirsch, Thomas Gladytz, Dirk Gutkelch, Kai Licha, Jörn Berger, Dirk Grosenick

JBO, Vol. 27, Issue 07, 074702, (June 2022) https://doi.org/10.1117/12.10.1117/1.JBO.27.7.074702

KEYWORDS: Luminescence, Absorption, Tissues, Scattering, Printing, 3D printing, Imaging systems, 3D modeling, Light scattering, Solids

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Significance: Fluorescence imaging of rheumatoid diseases with indocyanine green (ICG) is an emerging technique with unique potential for diagnosis and therapy. Device characterization, monitoring of the performance, and further developments of the technique require tissue-equivalent fluorescent phantoms of high stability with appropriate anatomical shapes. Aim: Our investigations aim at the development of a three-dimensional (3D) printing technique to fabricate hand and finger models with appropriate optical properties in the near-infrared spectral range. These phantoms should have fluorescence properties similar to ICG, and excellent photostability and durability over years. Approach: We modified a 3D printing methacrylate photopolymer by adding the fluorescent dye Lumogen IR 765 to the raw material. Reduced scattering and absorption coefficients were adjusted to values representative of the human hand by incorporating titanium dioxide powder and black ink. The properties of printed phantoms of various compositions were characterized using UV/Vis and fluorescence spectroscopy, and time-resolved measurements. Photostability and bleaching were investigated with a hand imager. For comparison, several phantoms with ICG as fluorescent dye were printed and characterized as well. Results: The spectral properties of Lumogen IR 765 are very similar to those of ICG. By optimizing the concentrations of Lumogen, titanium dioxide, and ink, anatomically shaped hand and vessel models with properties equivalent to in vivo investigations with a fluorescence hand imager could be printed. Phantoms with Lumogen IR 765 had an excellent photostability over up to 4 years. In contrast, phantoms printed with ICG showed significant bleaching and degradation of fluorescence over time. Conclusions: 3D printing of phantoms with Lumogen IR 765 is a promising method for fabricating anatomically shaped fluorescent tissue models of excellent stability with spectral properties similar to ICG. The phantoms are well-suited to monitor the performance of hand imagers. Concepts can easily be transferred to other fluorescence imaging applications of ICG.

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SPIE Journal Paper | 15 June 2022 Open Access

Multi-laboratory performance assessment of diffuse optics instruments: the BitMap exercise

Pranav Lanka, Lin Yang, David Orive-Miguel, Joshua Deepak Veesa, Susanna Tagliabue, Aleh Sudakou, Saeed Samaei, Mario Forcione, Zuzana Kovacsova, Anurag Behera, Thomas Gladytz, Dirk Grosenick, Lionel Hervé, Turgut Durduran, Karolina Bejm, Magdalena Morawiec, Michał Kacprzak, Piotr Sawosz, Anna Gerega, Adam Liebert, Antonio Belli, Ilias Tachtsidis, Frédéric Lange, Gemma Bale, Luca Baratelli, Sylvain Gioux, Alexander Kalyanov, Martin Wolf, Sanathana Konugolu-Venkata-Sekar, Marta Zanoletti, Ileana Pirovano, Michele Lacerenza, Lina Qiu, Edoardo Ferocino, Giulia Maffeis, Caterina Amendola, Lorenzo Colombo, Lorenzo Frabasile, Pietro Levoni, Mauro Buttafava, Marco Renna, Laura Di Sieno, Rebecca Re, Andrea Farina, Lorenzo Spinelli, Alberto Dalla Mora, Davide Contini, Paola Taroni, Alberto Tosi, Alessandro Torricelli, Hamid Dehghani, Heidrun Wabnitz, Antonio Pifferi

JBO, Vol. 27, Issue 07, 074716, (June 2022) https://doi.org/10.1117/12.10.1117/1.JBO.27.7.074716

KEYWORDS: Raster graphics, Optical properties, Diffuse optical imaging, Scattering, Imaging spectroscopy, Absorption, Tissue optics, Spectroscopes, Sensors, Oximetry

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Proceedings Article | 9 December 2021 Paper

Reconstruction of absorption maps by digital tomosynthesis

Nicolás Carbone, Demian Vera, Daniela Iriarte, Juan Pomarico, Rainer Macdonald, Dirk Grosenick

Proceedings Volume 11920, 1192015 (2021) https://doi.org/10.1117/12.2615346

KEYWORDS: Absorption, Data modeling, Tumor growth modeling, Optical spheres, Breast, Finite element methods, Scattering, Cameras, Algorithm development, Optical properties

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Proceedings Article | 9 December 2021 Paper

Determination of optical properties from spatially resolved diffuse reflectance using relative and absolute data

Hunain Farooq, Thomas Gladytz, Alexander Hoppe, Dirk Grosenick

Proceedings Volume 11920, 119200X (2021) https://doi.org/10.1117/12.2615259

KEYWORDS: Optical properties, Data analysis, Absorption, Diffuse reflectance spectroscopy, Reflectivity, Scattering, Calibration, Diodes, Avalanche photodiodes, Scanners

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Proceedings Article | 5 March 2021 Presentation + Paper

A multi-laboratory comparison of photon migration instruments and their performances: the BitMap exercise

Sri Rama Pranav Kumar Lanka, Lin Yang, David Orive-Miguel, Joshua Deepak Veesa, Susanna Tagliabue, Aleh Sudakou, Saeed Samaei, Mario Forcione, Zuzana Kovacsova, Anurag Behera, Thomas Gladytz, Dirk Grosenick, Lionel Hervé, Giuseppe Lo Presti, Lorenzo Cortese, Turgut Durduran, Karolina Bejm, Magdalena Morawiec, Piotr Sawosz, Michal Kacprzak, Anna Gerega, Adam Liebert, Antonio Belli, Ilias Tachtsidis, Frédéric Lange, Gemma Bale, Luca Baratelli, Sylvain Gioux, Alexander Kalyanov, Martin Wolf, Sanathana Konugolu Venkata Sekar, Marta Zanoletti, Ileana Pirovano, Michele Lacerenza, Lina Qiu, Edoardo Ferocino, Giulia Maffeis, Caterina Amendola, Lorenzo Colombo, Mauro Buttafava, Marco Renna, Laura Di Sieno, Rebecca Re, Andrea Farina, Lorenzo Spinelli, Alberto Dalla Mora, Davide Contini, Alessandro Torricelli, Alberto Tosi, Paola Taroni, Hamid Dehghani, Heidrun Wabnitz, Antonio Pifferi

Proceedings Volume 11639, 116390F (2021) https://doi.org/10.1117/12.2578521

KEYWORDS: Raster graphics, Photonic devices, Tissue optics, Spectroscopes, Oximetry, Optical components, Mammography, Imaging spectroscopy, Functional imaging

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Proceedings Article | 5 March 2021 Presentation

Accurate characterization of phantoms for performance assessment and calibration in diffuse optics

Heidrun Wabnitz, Lin Yang, Thomas Gladytz, Lina Hacker, James Joseph, Dirk Grosenick

Proceedings Volume 11633, 1163306 (2021) https://doi.org/10.1117/12.2588994

KEYWORDS: Diffuse optical imaging, Optical calibration, Calibration, Spatial light modulators, Reflectivity, Optical properties, Monte Carlo methods, Transmittance, Spectroscopes, Solids

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Proceedings Article | 11 July 2019 Paper

Three-dimensional printed tissue-simulating phantoms for fluorescence imaging

Sandra Schädel-Ebner, Katrin Schira, Ole Hirsch, Dirk Grosenick

Proceedings Volume 11074, 110742W (2019) https://doi.org/10.1117/12.2526969

KEYWORDS: Luminescence, Absorption, Scattering, 3D printing, Optical properties

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Proceedings Article | 11 July 2019 Paper

Spatially-enhanced time-domain NIRS for determination of optical properties in layered structures

Lin Yang, Pranav Lanka, Heidrun Wabnitz, Rinaldo Cubeddu, Thomas Gladytz, Sanathana Konugolu Venkata Sekar, Dirk Grosenick, Antonio Pifferi, Rainer Macdonald

Proceedings Volume 11074, 110740A (2019) https://doi.org/10.1117/12.2527032

KEYWORDS: Absorption, Near infrared spectroscopy, Optical properties, Scattering, Monte Carlo methods, Tissue optics, Tissues, Brain

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Proceedings Article | 11 July 2019 Paper

Extended Kalman Filtering for the recovery of the absorption coefficients in layered turbid media

Guido Baez, Héctor García, Dirk Grosenick, Heidrun Wabnitz

Proceedings Volume 11074, 110742N (2019) https://doi.org/10.1117/12.2527043

KEYWORDS: Absorption, Scattering, Reflectivity, Optical properties

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Proceedings Article | 11 July 2019 Paper

Towards depth-resolved characterization of hemodynamics and oxygenation in the rat kidney

Thomas Gladytz, Kathleen Cantow, Bert Flemming, Andreas Pohlmann, Thoralf Niendorf, Erdmann Seeliger, Dirk Grosenick

Proceedings Volume 11074, 1107415 (2019) https://doi.org/10.1117/12.2526943

KEYWORDS: Kidney, Transmittance, Reflectivity, Near infrared spectroscopy, Hemodynamics, Oxygen

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Proceedings Article | 4 March 2019 Presentation

Noise reduction and compression of Monte-Carlo lookup tables by singular value decomposition (Conference Presentation)

Thomas Gladytz, Heidrun Wabnitz, Lin Yang, Dirk Grosenick

Proceedings Volume 10870, 1087005 (2019) https://doi.org/10.1117/12.2506035

KEYWORDS: Monte Carlo methods, Denoising, Optical properties, Modeling, Near infrared spectroscopy, Statistical modeling, Absorption, Interference (communication), Smoothing, Sensors

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Proceedings Article | 1 March 2019 Paper

Near infrared spectroscopy system for quantitative monitoring of renal hemodynamics and oxygenation in rats

Thomas Gladytz, Alexander Hoppe, Kathleen Cantow, Bert Flemming, Andreas Pohlmann, Thoralf Niendorf, Erdmann Seeliger, Dirk Grosenick

Proceedings Volume 10874, 108740H (2019) https://doi.org/10.1117/12.2507371

KEYWORDS: Absorption, Kidney, Calibration, Near infrared spectroscopy, Optical properties, Scattering, Hemodynamics, Oxygen, Reflectivity

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Proceedings Article | 28 July 2017 Paper

Fluorescence-guided mapping of sentinel lymph nodes in gynecological malignancies

Ole Hirsch, Łukasz Szyc, Mustafa Zelal Muallem, Iulia Ignat, Radoslav Chekerov, Rainer Macdonald, Jalid Sehouli, Ioana Braicu, Dirk Grosenick

Proceedings Volume 10412, 104120L (2017) https://doi.org/10.1117/12.2285933

KEYWORDS: Lymphatic system, Luminescence, Cancer

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Proceedings Article | 28 July 2017 Paper

Retrieval of the optical properties in a semiinfinite three layers phantom: theory, experiments, and simulations

H. García, D. Iriarte, J. Pomarico, D. Grosenick, R. Macdonald

Proceedings Volume 10412, 104120S (2017) https://doi.org/10.1117/12.2285446

KEYWORDS: Optical properties, Multilayers, Reflection

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Proceedings Article | 28 July 2017 Paper

Tissue optical properties from spatially resolved reflectance: calibration and in vivo application on rat kidney

Thomas Gladytz, Alexander Hoppe, Kathleen Cantow, Bert Flemming, Andreas Pohlmann, Thoralf Niendorf, Erdmann Seeliger, Dirk Grosenick

Proceedings Volume 10412, 104120Q (2017) https://doi.org/10.1117/12.2285980

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Proceedings Article | 16 March 2017 Paper

Broadband spectral measurements of diffuse optical properties by an integrating sphere instrument at the National Institute of Standards and Technology

Paul Lemaillet, Jeeseong Hwang, Heidrun Wabnitz, Dirk Grosenick, Lin Yang, David Allen

Proceedings Volume 10056, 1005604 (2017) https://doi.org/10.1117/12.2263338

KEYWORDS: Indium oxide, Scattering, Optical properties, Integrating spheres, Reflectivity, Transmittance, Standards development, Optical testing, Optical spheres, Solids

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Proceedings Article | 15 March 2017 Paper

Polydimethylsiloxane tissue-mimicking phantoms for quantitative optical medical imaging standards

Jeeseong Hwang, Hyun-Jin Kim, Paul Lemaillet, Heidrun Wabnitz, Dirk Grosenick, Lin Yang, Thomas Gladytz, David McClatchy, David Allen, Kimberly Briggman, Brian Pogue

Proceedings Volume 10056, 1005603 (2017) https://doi.org/10.1117/12.2263379

KEYWORDS: Scattering, Particles, Confocal microscopy, Tissue optics, Light scattering, Integrating spheres, Tissues, Reflectivity, Standards development, Backscatter

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Proceedings Article | 14 March 2017 Paper

Reliable determination of tissue optical properties from spatially resolved reflectance

Thomas Gladytz, Alexander Hoppe, Kathleen Cantow, Andreas Pohlmann, Bert Flemming, Thoralf Niendorf, Erdmann Seeliger, Dirk Grosenick

Proceedings Volume 10056, 100560W (2017) https://doi.org/10.1117/12.2250552

KEYWORDS: Optical properties, Reflectivity, Tissue optics, Calibration, Scattering, Monte Carlo methods, Diffuse reflectance spectroscopy, Near infrared spectroscopy, Light scattering, Diffusion, Absorption, Kidney, Sensors, Data analysis

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Proceedings Article | 17 February 2017 Paper

Sentinel lymph node detection in gynecologic malignancies by a handheld fluorescence camera

Ole Hirsch, Lukasz Szyc, Mustafa Zelal Muallem, Iulia Ignat, Radoslav Chekerov, Rainer Macdonald, Jalid Sehouli, Ioana Braicu, Dirk Grosenick

Proceedings Volume 10059, 100591B (2017) https://doi.org/10.1117/12.2250723

KEYWORDS: Lymphatic system, Luminescence, Cancer, Imaging systems, Surgery, Cameras, Cervical cancer, Ovarian cancer, Tissues, Near infrared spectroscopy, Light emitting diodes

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SPIE Journal Paper | 11 July 2016 Open Access

Review of optical breast imaging and spectroscopy

Dirk Grosenick, Herbert Rinneberg, Rinaldo Cubeddu, Paola Taroni

JBO, Vol. 21, Issue 09, 091311, (July 2016) https://doi.org/10.1117/12.10.1117/1.JBO.21.9.091311

KEYWORDS: Breast, Tissue optics, Tumors, Tissues, Mammography, Scattering, Absorption, Breast imaging, Imaging spectroscopy, Spectroscopy

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Proceedings Article | 16 July 2015 Paper

CW fluorescence imaging of tissue-like media in reflectance geometry

N. Carbone, D. Iriarte, J. Pomarico, D. Grosenick, R. Macdonald

Proceedings Volume 9538, 95381E (2015) https://doi.org/10.1117/12.2183473

KEYWORDS: Absorption, Tissues, Image processing, Optical spheres, Luminescence, Scattering, Cameras, Near infrared, Modulation

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Proceedings Article | 16 July 2015 Paper

Time-resolved transmittance: a comparison of the diffusion model approach with Monte Carlo simulations

Ramona Rothfischer, Dirk Grosenick, Rainer Macdonald

Proceedings Volume 9538, 95381H (2015) https://doi.org/10.1117/12.2183762

KEYWORDS: Diffusion, Scattering, Monte Carlo methods, Absorption, Optical properties, Glasses, Transmittance, Data modeling, Solids, Picosecond phenomena

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Proceedings Article | 16 July 2015 Paper

Determination of the optical properties of multilayered phantoms by time-resolved reflectance measurements

H. García, D. Iriarte, J. Pomarico, D. Grosenick, R. Macdonald

Proceedings Volume 9538, 95381G (2015) https://doi.org/10.1117/12.2183459

KEYWORDS: Optical properties, Absorption, Reflectivity, Liquids, Solids, Tissues, Scattering, Diffusion, Multilayers, Head

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Proceedings Article | 16 July 2015 Paper

Monitoring hemodynamics and oxygenation of the kidney in rats by a combined near-infrared spectroscopy and invasive probe approach

Dirk Grosenick, Kathleen Cantow, Karen Arakelyan, Heidrun Wabnitz, Bert Flemming, Angela Skalweit, Mechthild Ladwig, Rainer Macdonald, Thoralf Niendorf, Erdmann Seeliger

Proceedings Volume 9538, 95380L (2015) https://doi.org/10.1117/12.2183417

KEYWORDS: Oxygen, Tissues, Kidney, Near infrared spectroscopy, Blood, Hypoxia, X-rays, Hemodynamics, Laser tissue interaction, Data modeling

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Proceedings Article | 5 March 2015 Paper

Characterization of hemodynamics and oxygenation in the renal cortex of rats

Dirk Grosenick, Heidrun Wabnitz, Rainer Macdonald, Thoralf Niendorf, Kathleen Cantow, Bert Flemming, Karen Arakelyan, Erdmann Seeliger

Proceedings Volume 9319, 93191C (2015) https://doi.org/10.1117/12.2076148

KEYWORDS: Oxygen, Tissues, Near infrared spectroscopy, Blood, Laser tissue interaction, Kidney, Hemodynamics, Hyperoxia, Hypoxia, Scattering

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SPIE Journal Paper | 13 January 2015 Open Access

Development of a handheld fluorescence imaging camera for intraoperative sentinel lymph node mapping

Lukasz Szyc, Stefanie Bonifer, Alfred Walter, Uwe Jagemann, Dirk Grosenick, Rainer Macdonald

JBO, Vol. 20, Issue 05, 051025, (January 2015) https://doi.org/10.1117/12.10.1117/1.JBO.20.5.051025

KEYWORDS: Luminescence, Lymphatic system, Absorption, Cameras, Tissues, Imaging systems, Reflectivity, Scattering, Tissue optics, Head

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Proceedings Article | 25 March 2013 Paper

Near-infrared spectroscopy of renal tissue in vivo

Dirk Grosenick, Oliver Steinkellner, Heidrun Wabnitz, Rainer Macdonald, Thoralf Niendorf, Kathleen Cantow, Bert Flemming, Erdmann Seeliger

Proceedings Volume 8578, 85781P (2013) https://doi.org/10.1117/12.2000409

KEYWORDS: Tissues, Kidney, Monte Carlo methods, Tissue optics, Oxygen, Optical properties, In vivo imaging, Absorption, Scattering, Diffuse reflectance spectroscopy

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Proceedings Article | 12 February 2008 Paper

Accelerated DOT reconstruction using multiple sub-volumes

Ronny Ziegler, Tim Nielsen, Dirk Grosenick, Oliver Steinkellner, Axel Hagen, Rainer Macdonald, Herbert Rinneberg

Proceedings Volume 6850, 68500A (2008) https://doi.org/10.1117/12.763458

KEYWORDS: Absorption, Sensors, Luminescence, Diffusion, Scattering, Reconstruction algorithms, Optical properties, Image processing, Breast, Diffuse optical tomography

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Proceedings Article | 13 February 2007 Paper

Development of a multi-channel time-domain fluorescence mammograph

A. Hagen, O. Steinkellner, D. Grosenick, M. Möller, R. Ziegler, T. Nielsen, K. Lauritsen, R. Macdonald, H. Rinneberg

Proceedings Volume 6434, 64340Z (2007) https://doi.org/10.1117/12.701010

KEYWORDS: Luminescence, Photons, Breast, Optical spheres, Sensors, Mammography, Scattering, Laser scattering, Tissue optics, Absorption

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Proceedings Article | 13 February 2007 Paper

Reconstruction of absorption and fluorescence contrast for scanning time-domain fluorescence mammography

Ronny Ziegler, Tim Nielsen, Thomas Koehler, Dirk Grosenick, Oliver Steinkellner, Axel Hagen, Rainer Macdonald, Herbert Rinneberg

Proceedings Volume 6434, 64340H (2007) https://doi.org/10.1117/12.700860

KEYWORDS: Luminescence, Absorption, Sensors, Scattering, Diffusion, Mammography, Reconstruction algorithms, Breast, Image restoration, Image transmission

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Proceedings Article | 13 February 2007 Paper

Phantom study on combined cw and time-domain fluorescence mammography

D. Grosenick, O. Steinkellner, A. Hagen, R. Ziegler, T. Nielsen, R. Macdonald, H. Rinneberg

Proceedings Volume 6434, 64340I (2007) https://doi.org/10.1117/12.700973

KEYWORDS: Luminescence, Absorption, Optical spheres, Photons, Cameras, Electron multiplying charge coupled devices, Sensors, Breast, Mammography

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Proceedings Article | 8 October 2005 Paper

Experimental assessment of analytical models for estimating tumor optical properties in laser pulse mammography

D. Grosenick, B. Wassermann, R. Macdonald, H. Rinneberg, A. Torricelli, L. Spinelli, R. Cubeddu

Proceedings Volume 5859, 58590M (2005) https://doi.org/10.1117/12.632842

KEYWORDS: Optical spheres, Absorption, Optical properties, Scattering, Diffraction, Data modeling, Tumors, Spherical lenses, Finite element methods, Breast

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Proceedings Article | 28 April 2005 Paper

Analysis of time-domain optical mammograms recorded from more than 150 patients

D. Grosenick, K. Moesta, M. Moller, H. Wabnitz, J. Mucke, B. Gebauer, B. Wassermann, G. Wubbeler, R. Macdonald, P. Schlag, H. Rinneberg

Proceedings Volume 5693, (2005) https://doi.org/10.1117/12.590348

KEYWORDS: Mammography, Tumors, Optical properties, Breast, Absorption, Tissues, Tissue optics, Tumor growth modeling, Scattering, Blood oxygen saturation

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Proceedings Article | 15 October 2003 Paper

Four-wavelength multichannel time-resolved optical mammograph

Michael Moeller, Heidrun Wabnitz, Andreas Kummrow, Dirk Grosenick, Adam Liebert, Bernhard Wassermann, Rainer Macdonald, Herbert Rinneberg

Proceedings Volume 5138, (2003) https://doi.org/10.1117/12.500649

KEYWORDS: Signal attenuation, Mammography, Sensors, Optical fibers, Breast, Scattering, Channel projecting optics, Tissue optics, Pulsed laser operation, Absorption

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Proceedings Article | 15 October 2003 Paper

Performance assessment of two time-domain-scanning optical mammographs

Heidrun Wabnitz, Paola Taroni, Dirk Grosenick, Antonio Pifferi, Alessandro Torricelli, Adam Liebert, Michael Moeller, Rinaldo Cubeddu, Herbert Rinneberg

Proceedings Volume 5138, (2003) https://doi.org/10.1117/12.500533

KEYWORDS: Optical properties, Mammography, Photon counting, Transmittance, Scattering, Time correlated photon counting, Tissue optics, Absorption, Solids, Imaging spectroscopy

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SPIE Journal Paper | 1 July 2003 Open Access

Fiber dispersion in time domain measurements compromising the accuracy of determination of optical properties of strongly scattering media

Adam Liebert, Heidrun Wabnitz, Dirk Grosenick, Rainer Macdonald

JBO, Vol. 8, Issue 03, (July 2003) https://doi.org/10.1117/12.10.1117/1.1578088

KEYWORDS: Optical properties, Scattering, Dispersion, Tissue optics, Picosecond phenomena, Glasses, Diffusers, Time metrology, Scattering media, Laser scattering

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SPIE Journal Paper | 1 January 2002 Open Access

Quantification of optical properties of a breast tumor using random walk theory

Victor Chernomordik, David Hattery, Dirk Grosenick, Heidrun Wabnitz, Herbert Rinneberg, K. Moesta, Peter Schlag, Amir Gandjbakhche

JBO, Vol. 7, Issue 01, (January 2002) https://doi.org/10.1117/12.10.1117/1.1427049

KEYWORDS: Tumors, Tissue optics, Breast, Absorption, Scattering, Optical properties, Photons, Tissues, Point spread functions, Data modeling

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Proceedings Article | 2 November 2001 Paper

High-count-rate multichannel TCSPC for optical tomography

Wolfgang Becker, Axel Bergmann, Heidrun Wabnitz, Dirk Grosenick, Adam Liebert

Proceedings Volume 4431, (2001) https://doi.org/10.1117/12.447430

KEYWORDS: Sensors, Photons, Mammography, Tissue optics, Scattering, Optical spheres, Optical tomography, Absorption, Signal detection, Pulsed laser operation

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SPIE Journal Paper | 1 April 2001 Open Access

Near-infrared fluorescent dyes for enhanced contrast in optical mammography: phantom experiments

Bernd Ebert, Uwe Sukowski, Dirk Grosenick, Heidrun Wabnitz, K. Moesta, Kai Licha, Andreas Becker, Wolfhard Semmler, Peter Schlag, Herbert Rinneberg

JBO, Vol. 6, Issue 02, (April 2001) https://doi.org/10.1117/12.10.1117/1.1350561

KEYWORDS: Luminescence, Tumors, Scattering, Tissues, Photons, Absorption, Tissue optics, Breast, Mammography, Modulation

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Proceedings Article | 6 December 1996 Paper

Fast time-resolved imaging of diffusely scattering solid phantoms for optical mammography

Dirk Grosenick, Harald Danlewski, Herbert Rinneberg

Proceedings Volume 2925, (1996) https://doi.org/10.1117/12.260848

KEYWORDS: Optical spheres, Signal to noise ratio, Scattering, Transmittance, Modulation, Photons, Phase shifts, Semiconductor lasers, Mammography, Solids

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Proceedings Article | 18 December 1995 Paper

Contrast and spatial resolution of time-resolved transillumination images

Dirk Grosenick, Heidrun Wabnitz, Herbert Rinneberg

Proceedings Volume 2626, (1995) https://doi.org/10.1117/12.228667

KEYWORDS: Transmittance, Signal to noise ratio, Photons, Modulation, Scattering, Phase shifts, Absorption, Time metrology, Solids, Optical properties

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Proceedings Article | 18 December 1995 Paper

Diffusely scattering phantoms for optical tomography

Uwe Sukowski, Florian Schubert, Dirk Grosenick, Herbert Rinneberg

Proceedings Volume 2626, (1995) https://doi.org/10.1117/12.228653

KEYWORDS: Scattering, Transmittance, Optical spheres, Mie scattering, Solids, Absorption, Collimation, Quartz, Glasses, Diffuse reflectance spectroscopy

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Showing 5 of 44 publications

Conference Committee Involvement (5)

Diffuse Optical Spectroscopy and Imaging

25 June 2023 | Munich, Germany

Diffuse Optical Spectroscopy and Imaging VIII

20 June 2021 | Online Only, Germany

Diffuse Optical Spectroscopy and Imaging VII

23 June 2019 | Munich, Germany

Diffuse Optical Spectroscopy and Imaging VI

25 June 2017 | Munich, Germany

Diffuse Optical Imaging V

23 June 2015 | Munich, Germany

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