Prof. Haishan Zeng
Professor at BC Cancer Research Institute
SPIE Involvement:
Conference Chair | Conference Program Committee | Editor | Author | Instructor
Area of Expertise:
Raman Spectroscopy , Multispectral Imaging , Multiphoton Imaging , Endoscopy , Fluorescence Imaging , Phototherapy
Websites:
Profile Summary

Haishan Zeng is a distinguished scientist with the Integrative Oncology Department (Imaging Unit) of the BC Cancer Agency Research Centre, Vancouver, Canada, a professor of Dermatology and Skin Science at the University of British Columbia (UBC), and associate member of UBC Departments of Pathology & Laboratory Medicine and Physics & Astronomy. Dr. Zeng received a B.Sc. degree on electronic physics from Peking University, a M.Sc. degree on electronic physics and devices from the Chinese Academy of Sciences, and a Ph.D. degree on biophysics from the University of British Columbia. For over 28 years, Dr. Zeng’s research has been focused on developing various optical imaging and spectroscopy techniques for improving early cancer detection. He has published over 151 refereed journal papers, 1 book, 17 book chapters, and has 25 granted patents related to optical diagnosis and therapy. Several medical devices derived from these patents including fluorescence endoscopy (ONCO-LIFE™) and rapid Raman spectroscopy (Verisante Aura™) have passed regulatory approvals and are currently in clinical uses around the world. The latest device, Verisante Aura™ using Raman spectroscopy for non-invasive skin cancer detection, was awarded the Prism Award in the Life Sciences and Biophotonics category in February, 2013 by SPIE, the International Society for Optics and Photonics.
Publications (96)

Proceedings Article | 13 March 2024 Presentation
Giselle Tian, Zhenguo Wu, Jianhua Zhao, Harvey Lui, Sunil Kalia, Haishan Zeng
Proceedings Volume PC12816, PC128160D (2024) https://doi.org/10.1117/12.3009063
KEYWORDS: Phototherapy, Skin, Ultraviolet radiation, Multiphoton microscopy, Monte Carlo methods, Confocal microscopy, Tissues, Reflectivity, Modeling, In vivo imaging

Proceedings Article | 13 March 2024 Presentation
Proceedings Volume PC12839, PC128390K (2024) https://doi.org/10.1117/12.3008762
KEYWORDS: Raman scattering, Raman spectroscopy, Photonic crystal fibers, Lung cancer, Cancer detection, Pulsed laser operation, Molecular interactions, Gases, Laser scattering, Continuous wave operation

Proceedings Article | 13 March 2024 Presentation
Shujian Li, Yunxian Tian, Zhenguo Wu, Jianhua Zhao, Harvey Lui, Sunil Kalia, Haishan Zeng
Proceedings Volume PC12816, PC1281605 (2024) https://doi.org/10.1117/12.3008995
KEYWORDS: Skin, Micro raman spectroscopy, Spectral response, Multiphoton microscopy, Tissues, Multimodal imaging, Imaging systems, Second harmonic generation, Laser therapeutics, In vivo imaging

Proceedings Article | 13 March 2024 Presentation
Zhenguo Wu, Tashmeeta Ahad, Sunil Kalia, Harvey Lui, Shujian Li, Jianhua Zhao, Haishan Zeng
Proceedings Volume PC12816, PC128160L (2024) https://doi.org/10.1117/12.3008997
KEYWORDS: Tissues, Skin, Natural surfaces, Scanners, Imaging systems, Confocal microscopy, Tumors, Surgery, Skin cancer, Second harmonic generation

Proceedings Article | 13 March 2024 Presentation
Jianhua Zhao, Harvey Lui, Sunil Kalia, Tim Lee, Haishan Zeng
Proceedings Volume PC12816, PC128160F (2024) https://doi.org/10.1117/12.3009005
KEYWORDS: Raman spectroscopy, Skin cancer, Machine learning, Lawrencium, Education and training, Cancer detection, Convolutional neural networks, Support vector machines, Statistical analysis, Skin

Showing 5 of 96 publications
Proceedings Volume Editor (19)

SPIE Conference Volume | 21 March 2024

SPIE Conference Volume | 14 April 2023

SPIE Conference Volume | 21 March 2022

SPIE Conference Volume | 22 April 2021

SPIE Conference Volume | 6 March 2020

Showing 5 of 19 publications
Conference Committee Involvement (25)
Photonics in Dermatology and Plastic Surgery 2025
25 January 2025 | San Francisco, California, United States
Tissue Optics and Photonics III
9 April 2024 | Strasbourg, France
Photonics in Dermatology and Plastic Surgery 2024
27 January 2024 | San Francisco, California, United States
Translational Biophotonics: Diagnostics and Therapeutics
25 June 2023 | Munich, Germany
Photonics in Dermatology and Plastic Surgery 2023
28 January 2023 | San Francisco, California, United States
Showing 5 of 25 Conference Committees
Course Instructor
SC823: Diagnostic Endoscopy
This course starts with an introduction to the basic optics, electronics, and mechanics of medical endoscopes. The course then concentrates on the principles of white light endoscopy, fluorescence endoscopy, and various methods of endoscopic spectroscopy including fluorescence, elastic scattering, and Raman (non-elastic) scattering. Microscopic endoscopy imaging such as OCT, confocal imaging, and multi-photon imaging will be briefly reviewed at the end. Example clinical applications of endoscopic optical imaging and spectroscopy techniques for lung cancer detection and localization are included throughout.
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